GPRASP1 and TACR2

Number of citations of the paper that reports this interaction (PMID 15452121)
38

Data Source:
HPRD (in vitro)

		GPRASP1	TACR2
Gene Name		G protein-coupled receptor associated sorting protein 1	tachykinin receptor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Tachykinin Receptor Activity Protein Binding Substance K Receptor Activity
	Biological Process	Endosome To Lysosome Transport G-protein Coupled Receptor Catabolic Process	Muscle Contraction Tachykinin Receptor Signaling Pathway Excretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Operant Conditioning Positive Regulation Of Vascular Permeability Response To Electrical Stimulus Prolactin Secretion Positive Regulation Of Uterine Smooth Muscle Contraction
Pathways			G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	4 interactors: GPRASP1 TAC1 TAC3 TAC4
Entrez ID		9737	6865
HPRD ID		02333	01207
Ensembl ID		ENSG00000198932	ENSG00000075073
Uniprot IDs		Q5JY77	P21452
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission Cytosolic Calcium Ion Homeostasis Regulation Of Smooth Muscle Contraction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Response To Stimulus Cellular Metal Ion Homeostasis Cell-cell Signaling Positive Regulation Of Smooth Muscle Contraction Cellular Cation Homeostasis Cellular Ion Homeostasis Signaling Signal Transduction Metal Ion Homeostasis Cell Communication Blood Circulation Cellular Chemical Homeostasis Ion Homeostasis Response To Stimulus Neuropeptide Signaling Pathway Regulation Of Muscle Contraction G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cellular Homeostasis Chemical Homeostasis Regulation Of Blood Pressure Tachykinin Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Opioid Receptor Signaling Pathway Regulation Of Vasoconstriction Positive Regulation Of Uterine Smooth Muscle Contraction Neurological System Process Homeostatic Process Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Blood Pressure Behavior Regulation Of CAMP Biosynthetic Process Sensory Perception Of Pain Regulation Of Secretion Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Regulation Of CAMP Metabolic Process Response To Abiotic Stimulus Regulation Of Adenylate Cyclase Activity	Tachykinin Receptor Signaling Pathway Positive Regulation Of Saliva Secretion Regulation Of Saliva Secretion Positive Regulation Of Digestive System Process Neuropeptide Signaling Pathway G-protein Coupled Receptor Catabolic Process Positive Regulation Of Corticosterone Secretion Regulation Of Blood Pressure G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Corticosterone Secretion Blood Circulation Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Secretion Positive Regulation Of Action Potential Negative Regulation Of Heart Rate Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Synaptic Transmission, GABAergic Insemination Receptor Catabolic Process Regulation Of Renal Sodium Excretion Copulation Negative Regulation Of Heart Contraction Regulation Of Excretion Regulation Of Secretion Positive Regulation Of Acute Inflammatory Response Endosome To Lysosome Transport Positive Regulation Of Transport Regulation Of Synaptic Transmission, GABAergic Response To Pain Response To Morphine Positive Regulation Of Stress Fiber Assembly Lysosomal Transport Long-term Memory Positive Regulation Of Actin Filament Bundle Assembly Cell Surface Receptor Signaling Pathway Mating Positive Regulation Of Lipid Transport Regulation Of Stress Fiber Assembly Regulation Of Acute Inflammatory Response Regulation Of Heart Rate Vacuolar Transport Positive Regulation Of Epithelial Cell Migration Receptor Metabolic Process Associative Learning Multicellular Organismal Response To Stress Sensory Perception Of Pain Response To Ammonium Ion Regulation Of Lipid Transport Positive Regulation Of Inflammatory Response
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