CLASP2 and FEZ1

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vitro)

		CLASP2	FEZ1
Gene Name		cytoplasmic linker associated protein 2	fasciculation and elongation protein zeta 1 (zygin I)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Cell Cortex Membrane Ruffle Membrane	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite
	Molecular Function	Protein Binding Galactoside 2-alpha-L-fucosyltransferase Activity Microtubule Plus-end Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Mitotic Nuclear Division Establishment Or Maintenance Of Cell Polarity Axon Guidance Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Fucosylation Cell Division	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus
Pathways		Role of Abl in Robo-Slit signaling Mitotic Prometaphase Axon guidance Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Signaling by Robo receptor Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		7 interactors: CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2	57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		23122	9638
HPRD ID		12054	09212
Ensembl ID		ENSG00000163539	ENSG00000149557
Uniprot IDs		B2RTR1 O75122	Q99689
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Microtubule Polymerization Mitotic Nuclear Division Cell Cycle Process Axon Guidance Regulation Of Microtubule Polymerization Or Depolymerization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Protein Transport Into Plasma Membrane Raft Positive Regulation Of Microtubule Plus-end Binding Regulation Of Microtubule-based Process Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Protein Localization To Plasma Membrane Raft Regulation Of Organelle Organization Neuron Development Cell Morphogenesis Protein Localization To Microtubule Neuron Differentiation Cell Projection Organization Protein Transport Into Membrane Raft Protein Localization To Membrane Raft Locomotion Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Polymerization Negative Regulation Of Macroautophagy Negative Regulation Of Microtubule Polymerization Establishment Of Mitochondrion Localization Movement Of Cell Or Subcellular Component Protein Transport Within Lipid Bilayer Cell Division Generation Of Neurons Protein Localization To Cytoskeleton Neurogenesis Regulation Of Cytoskeleton Organization Cell Development Response To External Stimulus Negative Regulation Of Autophagy Mitochondrion Localization Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation See more	Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated See more
Tagcloud ?		1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?