CLASP2 and CLIP1

Number of citations of the paper that reports this interaction (PMID 11290329)
107

Data Source:
HPRD (two hybrid, in vitro)

		CLASP2	CLIP1
Gene Name		cytoplasmic linker associated protein 2	CAP-GLY domain containing linker protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Cell Cortex Membrane Ruffle Membrane	Kinetochore Ruffle Cytoplasm Endosome Centrosome Cytosol Microtubule Cytoplasmic Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome
	Molecular Function	Protein Binding Galactoside 2-alpha-L-fucosyltransferase Activity Microtubule Plus-end Binding	Nucleic Acid Binding Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Protein Homodimerization Activity Metal Ion Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Mitotic Nuclear Division Establishment Or Maintenance Of Cell Polarity Axon Guidance Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Fucosylation Cell Division	Mitotic Cell Cycle Microtubule Bundle Formation Mitotic Nuclear Division Positive Regulation Of Microtubule Polymerization Protein Transport Into Plasma Membrane Raft
Pathways		Role of Abl in Robo-Slit signaling Mitotic Prometaphase Axon guidance Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Signaling by Robo receptor Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2	10 interactors: CALM1 CLASP2 DCTN1 IQGAP1 MAPRE1 MAPRE2 MTOR PAFAH1B1 TUBA1A TUBB
Entrez ID		23122	6249
HPRD ID		12054	01568
Ensembl ID		ENSG00000163539	ENSG00000130779
Uniprot IDs		B2RTR1 O75122	B3KXA5 P30622
PDB IDs			2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV
Enriched GO Terms of Interacting Partners?		Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Microtubule Polymerization Mitotic Nuclear Division Cell Cycle Process Axon Guidance Regulation Of Microtubule Polymerization Or Depolymerization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Protein Transport Into Plasma Membrane Raft Positive Regulation Of Microtubule Plus-end Binding Regulation Of Microtubule-based Process Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Protein Localization To Plasma Membrane Raft Regulation Of Organelle Organization Neuron Development Cell Morphogenesis Protein Localization To Microtubule Neuron Differentiation Cell Projection Organization Protein Transport Into Membrane Raft Protein Localization To Membrane Raft Locomotion Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Polymerization Negative Regulation Of Macroautophagy Negative Regulation Of Microtubule Polymerization Establishment Of Mitochondrion Localization Movement Of Cell Or Subcellular Component Protein Transport Within Lipid Bilayer Cell Division Generation Of Neurons Protein Localization To Cytoskeleton Neurogenesis Regulation Of Cytoskeleton Organization Cell Development Response To External Stimulus Negative Regulation Of Autophagy Mitochondrion Localization Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Division Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Cytoskeleton-dependent Intracellular Transport Cell Cycle Organelle Organization Microtubule-based Process Cellular Localization Protein Polymerization Microtubule Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Cellular Protein Complex Assembly Positive Regulation Of Protein Modification Process Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Carbohydrate Utilization Cellular Response To Organic Substance Regulation Of Protein Phosphorylation Establishment Of Localization In Cell Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Cytoskeleton Organization Cell Projection Organization Positive Regulation Of Kinase Activity Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Immune System Process Response To Calcium Ion Positive Regulation Of Protein Metabolic Process Regulation Of Ras GTPase Activity Microtubule-based Transport Positive Regulation Of Microtubule Plus-end Binding Establishment Of Centrosome Localization Regulation Of Dephosphorylation
Tagcloud ?		1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed	clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Difference) ?		1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed	clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Intersection) ?		microtubule