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PTPRH
Description
protein tyrosine phosphatase receptor type H
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Microvillus
Membrane
Apical Plasma Membrane
Nuclear Speck
Microvillus Membrane
Cell Projection
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Hydrolase Activity
Cadherin Binding
Biological Process
Protein Dephosphorylation
Apoptotic Process
Signal Transduction
Axon Guidance
Pathways
Drugs
Diseases
GWAS
Mean spheric corpuscular volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
)
Plateletcrit (
27863252
32888494
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Serum metabolite levels (
33031748
)
Systemic lupus erythematosus (
28714469
)
Novel Interacting Genes
1 novel interacting genes:
LAIR1
Interacting Genes
16 interacting genes:
BCAR1
CNKSR1
CRK
DHPS
DOK1
EGFR
ERBB3
ERBB4
GHR
KRTAP10-3
KRTAP10-8
LCK
MAPK1
MLH1
PTK2
PXN
Entrez ID
5794
HPRD ID
03942
Ensembl ID
ENSG00000080031
Uniprot IDs
Q9HD43
PDB IDs
7XC0
Enriched GO Terms of Interacting Partners
?
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
ERBB2 Signaling Pathway
Cell Surface Receptor Signaling Pathway
Protein Phosphatase Binding
SH2 Domain Binding
Protein Tyrosine Kinase Activity
Protein Tyrosine Kinase Activator Activity
Signal Transduction
Regulation Of MAPK Cascade
Growth Hormone Receptor Signaling Pathway
Epidermal Growth Factor Receptor Activity
Neuregulin Receptor Activity
Positive Regulation Of MAPK Cascade
Protein Kinase Activity
Positive Regulation Of Macrophage Proliferation
Response To Growth Factor
Phosphotyrosine Residue Binding
Cell Migration
Positive Regulation Of Cell Population Proliferation
Peptidyl-tyrosine Phosphorylation
Regulation Of Immune Response
Kinase Activity
Response To Epidermal Growth Factor
B Cell Receptor Signaling Pathway
Signal Complex Assembly
ERBB2-ERBB3 Signaling Pathway
ERBB3 Signaling Pathway
Cell Motility
Receptor Complex
Basal Plasma Membrane
Immune Response-regulating Signaling Pathway
Focal Adhesion
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Immune System Process
Positive Regulation Of Protein Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Growth
Positive Regulation Of Phosphorylation
Response To Hepatocyte Growth Factor
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Schwann Cell Development
Positive Regulation Of Cell Migration
T Cell Receptor Signaling Pathway
Tagcloud
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