PTPRH and DHPS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTPRH	DHPS
Gene Name		protein tyrosine phosphatase, receptor type, H	deoxyhypusine synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane	Cytosol
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding Deoxyhypusine Synthase Activity
	Biological Process	Protein Dephosphorylation Apoptotic Process Peptidyl-tyrosine Dephosphorylation	Translation Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of T Cell Proliferation Glucose Homeostasis Post-translational Protein Modification Cellular Protein Metabolic Process Deoxyhypusine Biosynthetic Process From Spermidine Protein Homotetramerization
Pathways			Post-translational protein modification Hypusine synthesis from eIF5A-lysine Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs			Nicotinamide-Adenine-Dinucleotide 1-Guanidinium-7-Aminoheptane
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BCAR1 DHPS DOK1 GHR KRTAP10-3 KRTAP10-8 LCK MAPK1 MLH1 PTK2 PXN	13 interactors: BRCA1 EIF5A EIF5A2 MAPK3 NIF3L1 NUDT18 PTPRH RAB27B REL RPL9 VASH1 WDYHV1 ZNF138
Entrez ID		5794	1725
HPRD ID		03942	02969
Ensembl ID		ENSG00000080031	ENSG00000095059
Uniprot IDs		C9JCH2 Q9HD43	P49366
PDB IDs			1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Hormone Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Growth Hormone Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Organonitrogen Compound Enzyme Linked Receptor Protein Signaling Pathway Response To Hormone Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification B Cell Receptor Signaling Pathway Platelet Activation Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Peptidyl-tyrosine Phosphorylation Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Signal Complex Assembly Response To Organic Substance Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Positive Regulation Of Immune System Process Integrin-mediated Signaling Pathway Blood Coagulation Hemostasis Antigen Receptor-mediated Signaling Pathway Activation Of MAPK Activity Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Regulation Of Protein Phosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Kinase Activity Insulin Receptor Signaling Pathway Cellular Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Positive Regulation Of Transferase Activity	Translational Frameshifting Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Termination Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Protein Complex Disassembly Translational Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone Acetylation Positive Regulation Of Protein Metabolic Process Negative Regulation Of Lymphangiogenesis Positive Regulation Of Histone H4-K20 Methylation DGDP Catabolic Process DADP Catabolic Process Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Apolipoprotein Binding Polyamine Homeostasis GDP Catabolic Process Positive Regulation Of Histone Modification Positive Regulation Of Translation Positive Regulation Of Histone H3-K9 Acetylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Apoptotic Process Macromolecule Biosynthetic Process Dihydrobiopterin Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Programmed Cell Death MRNA Transport Cell Death Regulation Of Protein Complex Disassembly Death Regulation Of Histone Modification Multivesicular Body Sorting Pathway Regulation Of Golgi Inheritance Positive Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process RNA Transport Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Cellular Response To Indole-3-methanol RNA Localization
Tagcloud ?			administrations antihypertensive blocker cas ceb curves diastolic dihydropyridine dihydropyridines dogs exerted felodipine hypertensive intravenous lasting lercanidipine nicardipine nitrendipine orally potency rec reference repeated shr spontaneously starting systolic tachyphylaxis
Tagcloud (Difference) ?			administrations antihypertensive blocker cas ceb curves diastolic dihydropyridine dihydropyridines dogs exerted felodipine hypertensive intravenous lasting lercanidipine nicardipine nitrendipine orally potency rec reference repeated shr spontaneously starting systolic tachyphylaxis
Tagcloud (Intersection) ?