TJP2 and CLDN2

Number of citations of the paper that reports this interaction (PMID 22731716)
1

Data Source:
BioGRID (two hybrid)

		TJP2	CLDN2
Gene Name		tight junction protein 2	claudin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Tight Junction Cell Junction	Plasma Membrane Tight Junction Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Guanylate Kinase Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Protein Binding, Bridging	Structural Molecule Activity Identical Protein Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Organic Substance Hippo Signaling Nucleotide Phosphorylation Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Pathways		Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Signaling by Hippo Programmed Cell Death Apoptotic execution phase	Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		Refractive error ( 23396134) Renal sinus fat ( 22044751)	Pancreatitis ( 23143602)
Protein-Protein Interactions		15 interactors: CDK6 CGN CLDN1 CLDN2 CTNNA1 EPB41 HGS OCLN SAFB SCRIB SH3KBP1 TJP1 YWHAB YWHAG YWHAZ	10 interactors: KRT31 KRTAP10-3 KRTAP4-12 LNX1 NOTCH2NL PIAS2 TJP1 TJP2 UBE2I WNK4
Entrez ID		9414	9075
HPRD ID		06369	06471
Ensembl ID		ENSG00000119139	ENSG00000165376
Uniprot IDs		B7Z2R3 B7Z954 Q9UDY2	P57739
PDB IDs		2OSG 3E17
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell-cell Junction Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Cell Junction Assembly Positive Regulation Of Apoptotic Signaling Pathway Apical Junction Assembly Positive Regulation Of Mitochondrion Organization Epithelial Cell Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Mitochondrion Organization Signaling Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Communication Protein Targeting Membrane Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Hippo Signaling Enzyme Linked Receptor Protein Signaling Pathway Intrinsic Apoptotic Signaling Pathway Signal Transduction Epithelial Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Tight Junction Assembly Positive Regulation Of Intracellular Transport Negative Regulation Of ERBB Signaling Pathway Cell Development Cell Adhesion Cellular Component Assembly Protein Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Cell Dedifferentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Signal Transduction Positive Regulation Of Transport Cellular Protein Localization Execution Phase Of Apoptosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Integrin-mediated Signaling Pathway	Establishment Of Endothelial Intestinal Barrier Protein Sumoylation Establishment Of Endothelial Barrier Hippo Signaling Endothelial Cell Development Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epithelium Development Execution Phase Of Apoptosis Endothelial Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Positive Regulation Of SUMO Transferase Activity Endothelium Development Protein Modification By Small Protein Conjugation Distal Tubule Morphogenesis Response To Magnetism Renal Sodium Ion Absorption Tissue Development Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Epithelial Cell Development Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-lysine Modification Renal Absorption Negative Regulation Of Androgen Receptor Signaling Pathway Distal Tubule Development Negative Regulation Of Vascular Permeability
Tagcloud ?			adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight tjp3 transam transcriptomic tubule uncovered utilizing
Tagcloud (Difference) ?			adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight tjp3 transam transcriptomic tubule uncovered utilizing
Tagcloud (Intersection) ?