TJP2 and SAFB

Number of citations of the paper that reports this interaction (PMID 12403786)
31

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TJP2	SAFB
Gene Name		tight junction protein 2	scaffold attachment factor B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Tight Junction Cell Junction	Nucleus Nucleoplasm
	Molecular Function	Guanylate Kinase Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Protein Binding, Bridging	Nucleotide Binding Core Promoter Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Organic Substance Hippo Signaling Nucleotide Phosphorylation Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability	Chromatin Organization Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Growth Hormone Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Signaling by Hippo Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Refractive error ( 23396134) Renal sinus fat ( 22044751)
Protein-Protein Interactions		15 interactors: CDK6 CGN CLDN1 CLDN2 CTNNA1 EPB41 HGS OCLN SAFB SCRIB SH3KBP1 TJP1 YWHAB YWHAG YWHAZ	21 interactors: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MAP1LC3B NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRSF9 TAF15 TJP2
Entrez ID		9414	6294
HPRD ID		06369	04205
Ensembl ID		ENSG00000119139	ENSG00000160633
Uniprot IDs		B7Z2R3 B7Z954 Q9UDY2	Q15424
PDB IDs		2OSG 3E17
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell-cell Junction Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Cell Junction Assembly Positive Regulation Of Apoptotic Signaling Pathway Apical Junction Assembly Positive Regulation Of Mitochondrion Organization Epithelial Cell Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Mitochondrion Organization Signaling Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Communication Protein Targeting Membrane Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Hippo Signaling Enzyme Linked Receptor Protein Signaling Pathway Intrinsic Apoptotic Signaling Pathway Signal Transduction Epithelial Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Tight Junction Assembly Positive Regulation Of Intracellular Transport Negative Regulation Of ERBB Signaling Pathway Cell Development Cell Adhesion Cellular Component Assembly Protein Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Cell Dedifferentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Signal Transduction Positive Regulation Of Transport Cellular Protein Localization Execution Phase Of Apoptosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Integrin-mediated Signaling Pathway	RNA Splicing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Metabolic Process DNA-templated Transcription, Initiation Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Viral Process Rhythmic Process Chromatin Modification Metabolic Process Chromosome Organization Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated DNA Conformation Change Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Interleukin-7-mediated Signaling Pathway Transcription, RNA-templated Positive Regulation Of Viral Process RNA Export From Nucleus Execution Phase Of Apoptosis
Tagcloud ?			array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Difference) ?			array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Intersection) ?