CLDN2

Gene Name		claudin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Tight Junction Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Identical Protein Binding
	Biological Process	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		Pancreatitis ( 23143602)
Protein-protein Interactions		10 interactors: KRT31 KRTAP10-3 KRTAP4-12 LNX1 NOTCH2NL PIAS2 TJP1 TJP2 UBE2I WNK4
Entrez ID		9075
HPRD ID		06471
Ensembl ID		ENSG00000165376
Uniprot IDs		P57739
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Intestinal Barrier Protein Sumoylation Establishment Of Endothelial Barrier Hippo Signaling Endothelial Cell Development Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epithelium Development Execution Phase Of Apoptosis Endothelial Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Positive Regulation Of SUMO Transferase Activity Endothelium Development Protein Modification By Small Protein Conjugation Distal Tubule Morphogenesis Response To Magnetism Renal Sodium Ion Absorption Tissue Development Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Epithelial Cell Development Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-lysine Modification Renal Absorption Negative Regulation Of Androgen Receptor Signaling Pathway Distal Tubule Development Negative Regulation Of Vascular Permeability
Tagcloud ?		adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight tjp3 transam transcriptomic tubule uncovered utilizing