CLDN2

Name	claudin 2
Structure
Interactors	29 interactors: ADAM33 BTN3A2 CLEC2D CSGALNACT2 CXCL9 CYSRT1 EMP3 FAM209A GRM2 IGFBP5 IL27RA KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP4-12 LAT LNX1 LPAR3 MTDH NOTCH2NLA PIAS2 PLP1 TEX264 TJP1 TJP2 TMEM218 UBE2I WNK4
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction Tight Junction Anchoring Junction
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding Paracellular Tight Junction Channel Activity
	Biological Process	Innate Immune Response In Mucosa Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Cell-cell Adhesion Regulation Of Bile Acid Secretion Paracellular Transport Regulation Of Intestinal D-glucose Absorption Regulation Of Intestinal Lipid Absorption
Pathways	Tight junction interactions
GWAS	Alcoholic chronic pancreatitis ( 28754779 ) Pancreatitis ( 23143602 )
Entrez ID	9075
HPRD ID	06471
Ensembl ID	ENSG00000165376
Uniprot IDs	P57739
PDB IDs	4YYX
GO Terms Enriched among Interactors ?	Keratin Filament Intermediate Filament Positive Regulation Of Blood-brain Barrier Permeability Bicellular Tight Junction Regulation Of Blood-brain Barrier Permeability Bleb Assembly Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Vascular Permeability