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TJP2 and CTNNA1
Number of citations of the paper that reports this interaction (PMID
10026224
)
48
Data Source:
HPRD
(in vitro)
TJP2
CTNNA1
Gene Name
tight junction protein 2
catenin (cadherin-associated protein), alpha 1, 102kDa
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Tight Junction
Cell Junction
Acrosomal Vesicle
Cytosol
Plasma Membrane
Cell-cell Junction
Zonula Adherens
Focal Adhesion
Intercalated Disc
Actin Cytoskeleton
Catenin Complex
Lamellipodium
Molecular Function
Guanylate Kinase Activity
Protein Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Protein Binding, Bridging
Structural Molecule Activity
Protein Binding
Beta-catenin Binding
Vinculin Binding
Poly(A) RNA Binding
Gamma-catenin Binding
Cadherin Binding
Actin Filament Binding
Biological Process
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Response To Organic Substance
Hippo Signaling
Nucleotide Phosphorylation
Intestinal Absorption
Establishment Of Endothelial Intestinal Barrier
Regulation Of Membrane Permeability
Ovarian Follicle Development
Actin Filament Organization
Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Negative Regulation Of Neuroblast Proliferation
Aging
Male Gonad Development
Gap Junction Assembly
Axon Regeneration
Cell Junction Assembly
Adherens Junction Organization
Cellular Protein Localization
Odontogenesis Of Dentin-containing Tooth
Muscle Cell Differentiation
Apical Junction Assembly
Response To Estrogen
Cell-cell Junction Organization
Positive Regulation Of Smoothened Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Muscle Cell Differentiation
Protein Heterooligomerization
Cellular Response To Indole-3-methanol
Epithelial Cell-cell Adhesion
Negative Regulation Of Cell Motility
Negative Regulation Of Integrin-mediated Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Apoptotic cleavage of cell adhesion proteins
Apoptotic cleavage of cellular proteins
Signaling by Hippo
Programmed Cell Death
Apoptotic execution phase
Cell junction organization
Cell-cell junction organization
CDO in myogenesis
Myogenesis
Signaling by VEGF
Adherens junctions interactions
VEGFR2 mediated vascular permeability
VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS
Refractive error (
23396134
)
Renal sinus fat (
22044751
)
Protein-Protein Interactions
15 interactors:
CDK6
CGN
CLDN1
CLDN2
CTNNA1
EPB41
HGS
OCLN
SAFB
SCRIB
SH3KBP1
TJP1
YWHAB
YWHAG
YWHAZ
27 interactors:
ACTN1
AJUBA
APC
APP
ARMC8
CA9
CDH1
CDH15
CDH2
CDH3
CDH5
CTBP1
CTNNB1
DLG1
FAM84B
JUP
MLLT4
PKD1
PSEN1
RNF219
SPTAN1
SPTBN1
SUMO1
TJP1
TJP2
VCL
ZGPAT
Entrez ID
9414
1495
HPRD ID
06369
00285
Ensembl ID
ENSG00000119139
ENSG00000044115
Uniprot IDs
B7Z2R3
B7Z954
Q9UDY2
P35221
PDB IDs
2OSG
3E17
1H6G
4EHP
4IGG
Enriched GO Terms of Interacting Partners
?
Cell-cell Junction Organization
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Cell-cell Junction Assembly
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Apoptotic Process
Programmed Cell Death
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cell Death
Death
Cell Junction Assembly
Positive Regulation Of Apoptotic Signaling Pathway
Apical Junction Assembly
Positive Regulation Of Mitochondrion Organization
Epithelial Cell Development
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Mitochondrion Organization
Signaling
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Cell Communication
Protein Targeting
Membrane Organization
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Hippo Signaling
Enzyme Linked Receptor Protein Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Signal Transduction
Epithelial Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tight Junction Assembly
Positive Regulation Of Intracellular Transport
Negative Regulation Of ERBB Signaling Pathway
Cell Development
Cell Adhesion
Cellular Component Assembly
Protein Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell-cell Signaling Involved In Cell-cell Junction Organization
Cell Dedifferentiation
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Regulation Of Signal Transduction
Positive Regulation Of Transport
Cellular Protein Localization
Execution Phase Of Apoptosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Apoptotic Signaling Pathway
Negative Regulation Of Integrin-mediated Signaling Pathway
Cell Junction Assembly
Cell-cell Junction Organization
Adherens Junction Organization
Cell Adhesion
Cellular Component Assembly
Epithelium Development
Developmental Process
Anatomical Structure Development
Cell-cell Junction Assembly
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Single Organismal Cell-cell Adhesion
Execution Phase Of Apoptosis
Adherens Junction Assembly
Cell Differentiation
Tissue Development
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Cell-cell Adhesion
Cell Development
Cellular Response To Indole-3-methanol
Establishment Of Endothelial Barrier
Apical Junction Assembly
Anatomical Structure Morphogenesis
Establishment Of Endothelial Intestinal Barrier
Regulation Of Protein Complex Assembly
Regulation Of Cellular Process
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Skin Development
Regulation Of Signal Transduction
Movement Of Cell Or Subcellular Component
Endothelial Cell Development
Tight Junction Assembly
Positive Regulation Of Protein Metabolic Process
Locomotion
Endomembrane System Organization
Neurogenesis
Apoptotic Process
Regulation Of Epithelial Cell Proliferation
Regulation Of Signaling
Cell Morphogenesis Involved In Differentiation
Programmed Cell Death
Morphogenesis Of An Epithelium
Cell Death
Death
Cell-matrix Adhesion
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Cellular Protein Metabolic Process
Endothelial Cell Differentiation
Neuron Differentiation
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Protein Localization
Tagcloud
?
alphae
alphat
cardiomyocyte
cardiomyocytes
catenin
catenins
coactivator
contractility
cre
delete
divide
dying
gained
heart
hearts
injured
knockout
lose
perinatal
proof
rationale
regulators
replace
shortly
transgenes
unable
yap
yes
Tagcloud (Difference)
?
alphae
alphat
cardiomyocyte
cardiomyocytes
catenin
catenins
coactivator
contractility
cre
delete
divide
dying
gained
heart
hearts
injured
knockout
lose
perinatal
proof
rationale
regulators
replace
shortly
transgenes
unable
yap
yes
Tagcloud (Intersection)
?