Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
FAM189A2 and WWP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
FAM189A2
WWP2
Gene Name
family with sequence similarity 189, member A2
WW domain containing E3 ubiquitin protein ligase 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Integral Component Of Membrane
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Membrane
Extracellular Vesicular Exosome
Molecular Function
Molecular_function
RNA Polymerase II Transcription Factor Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Ligase Activity
Biological Process
Biological_process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Transporter Activity
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Negative Regulation Of Protein Transport
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS
IgE levels (
23146381
)
Protein-Protein Interactions
9 interactors:
BAG3
CALCOCO2
SFN
STAM2
TAX1BP1
UBQLN1
UBXN1
WWP1
WWP2
53 interactors:
ANKRD44
ARRDC1
ATN1
CDC34
CLCN5
CPSF6
DAG1
DIDO1
EGR2
EWSR1
FAM189A2
FBXL18
HNRNPUL1
IL2RG
IL6R
LGALS9B
NDFIP2
PAIP1
PDLIM7
POLR2A
POU5F1
RASA1
RNF11
RUSC1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SF1
SFTPC
SMAD3
SMAD7
SNRPC
SPG20
TFAP2A
TNK2
TP53BP2
TRAF4
UBC
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2J2
UBE2K
UBE2L3
USP7
VASP
VPS37C
WBP1
WBP2
WIPF1
Entrez ID
9413
11060
HPRD ID
16255
03812
Ensembl ID
ENSG00000135063
ENSG00000198373
Uniprot IDs
Q15884
Q8WU02
B4DHF6
O00308
PDB IDs
Enriched GO Terms of Interacting Partners
?
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Viral Entry Into Host Cell
Entry Into Host Cell
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Interaction With Host
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Regulation Of Epidermal Cell Division
Protein Catabolic Process
Regulation Of Apoptotic Process
Regulation Of Cell Death
Viral Life Cycle
Regulation Of Protein Ubiquitination
Cellular Macromolecule Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Keratinocyte Development
Negative Regulation Of Keratinocyte Proliferation
Apoptotic Process
Negative Regulation Of Cell Death
Negative Regulation Of Cellular Metabolic Process
Programmed Cell Death
Positive Regulation Of Protein Export From Nucleus
Regulation Of Metabolic Process
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Cell Death
Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Establishment Of Skin Barrier
Apoptotic Signaling Pathway
Negative Regulation Of Proteolysis
Regulation Of Water Loss Via Skin
Negative Regulation Of Protein Processing
Positive Regulation Of Epidermal Cell Differentiation
Regulation Of Keratinocyte Proliferation
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Processing
Response To Stimulus
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Protein K63-linked Ubiquitination
Regulation Of Protein Export From Nucleus
Release Of Cytochrome C From Mitochondria
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Response To Stimulus
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Excretion
Response To Organic Substance
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Protein K11-linked Ubiquitination
Sodium Ion Homeostasis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Gene Expression
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stimulus
Positive Regulation Of Ossification
Regulation Of Ossification
RNA Biosynthetic Process
Regulation Of Protein Ubiquitination
Apoptotic Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Regulation Of Cellular Protein Metabolic Process
Viral Process
Apoptotic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Protein Catabolic Process
RNA Processing
Multicellular Organismal Water Homeostasis
Programmed Cell Death
Negative Regulation Of Transcription By Competitive Promoter Binding
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Proteolysis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Difference)
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Intersection)
?