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FAM189A2 and SFN
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
FAM189A2
SFN
Gene Name
family with sequence similarity 189, member A2
stratifin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Integral Component Of Membrane
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Vesicle Membrane
Extracellular Vesicular Exosome
Molecular Function
Molecular_function
Protein Binding
Protein Kinase C Inhibitor Activity
Protein Kinase Binding
Protein Domain Specific Binding
Phosphoprotein Binding
Biological Process
Biological_process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Release Of Cytochrome C From Mitochondria
Keratinocyte Development
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Signal Transduction
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Epidermal Cell Division
Negative Regulation Of Keratinocyte Proliferation
Positive Regulation Of Cell Growth
Keratinization
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Epidermal Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Membrane Organization
Establishment Of Skin Barrier
Negative Regulation Of Protein Serine/threonine Kinase Activity
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Programmed Cell Death
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
BAG3
CALCOCO2
SFN
STAM2
TAX1BP1
UBQLN1
UBXN1
WWP1
WWP2
49 interactors:
ABL1
BAD
BAX
BCR
CCAR1
CCDC102B
CCNH
CDC25B
CDK1
CHST1
EEF1A1
EGFR
EIF2S1
EIF4B
EXO1
FAM189A2
FAM53C
FAM9B
FOXO4
GPRIN2
HDAC5
HNRNPD
ING1
KCNK15
KCNK3
KCNK9
KIAA0408
LONRF1
MAGEA1
MAP3K5
MARK3
MDM4
MKRN3
MST1R
NR3C1
PLEKHF2
PLK4
RAB3IP
RFFL
RFWD2
SAMSN1
TBL3
TP53
TRIM25
TSC2
WDYHV1
YWHAG
ZC2HC1C
ZFP36
Entrez ID
9413
2810
HPRD ID
16255
03185
Ensembl ID
ENSG00000135063
ENSG00000175793
Uniprot IDs
Q15884
Q8WU02
P31947
PDB IDs
1YWT
1YZ5
3IQJ
3IQU
3IQV
3LW1
3MHR
3O8I
3P1N
3P1O
3P1P
3P1Q
3P1R
3P1S
3SMK
3SML
3SMM
3SMN
3SMO
3SPR
3T0L
3T0M
3U9X
3UX0
4DAT
4DAU
4DHM
4DHN
4DHO
4DHP
4DHQ
4DHR
4DHS
4DHT
4DHU
4FR3
4HQW
4HRU
4IEA
4JC3
4JDD
Enriched GO Terms of Interacting Partners
?
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Viral Entry Into Host Cell
Entry Into Host Cell
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Interaction With Host
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Regulation Of Epidermal Cell Division
Protein Catabolic Process
Regulation Of Apoptotic Process
Regulation Of Cell Death
Viral Life Cycle
Regulation Of Protein Ubiquitination
Cellular Macromolecule Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Keratinocyte Development
Negative Regulation Of Keratinocyte Proliferation
Apoptotic Process
Negative Regulation Of Cell Death
Negative Regulation Of Cellular Metabolic Process
Programmed Cell Death
Positive Regulation Of Protein Export From Nucleus
Regulation Of Metabolic Process
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Cell Death
Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Establishment Of Skin Barrier
Apoptotic Signaling Pathway
Negative Regulation Of Proteolysis
Regulation Of Water Loss Via Skin
Negative Regulation Of Protein Processing
Positive Regulation Of Epidermal Cell Differentiation
Regulation Of Keratinocyte Proliferation
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Processing
Response To Stimulus
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Protein K63-linked Ubiquitination
Regulation Of Protein Export From Nucleus
Release Of Cytochrome C From Mitochondria
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Neuron Death
Cell Cycle
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Phosphorylation
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Kinase Activity
Cellular Response To Organonitrogen Compound
Regulation Of Phosphorus Metabolic Process
Cell Cycle Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Mitotic Cell Cycle Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Intracellular Signal Transduction
ERBB Signaling Pathway
Regulation Of Protein Kinase Activity
Response To Stress
Mitotic Cell Cycle
Positive Regulation Of Cell Cycle
Response To Organic Substance
Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Cycle
Positive Regulation Of Protein Metabolic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Catalytic Activity
Cellular Response To Insulin Stimulus
G2/M Transition Of Mitotic Cell Cycle
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Mitotic Cell Cycle
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Response To Hormone
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Regulation Of Intracellular Signal Transduction
Cellular Response To Hormone Stimulus
Regulation Of Cell Proliferation
B Cell Activation
Fc Receptor Signaling Pathway
Tagcloud
?
aging
alarm
amplitude
auditory
circuits
cortico
elderly
electrophysiologically
employed
false
finding
frontal
impairments
latency
limbic
memory
n4
p3
perform
position
potentials
prefrontal
recency
serial
sternberg
subjects
task
working
young
Tagcloud (Difference)
?
aging
alarm
amplitude
auditory
circuits
cortico
elderly
electrophysiologically
employed
false
finding
frontal
impairments
latency
limbic
memory
n4
p3
perform
position
potentials
prefrontal
recency
serial
sternberg
subjects
task
working
young
Tagcloud (Intersection)
?