FAM189A2 and UBXN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM189A2	UBXN1
Gene Name		family with sequence similarity 189, member A2	UBX domain protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Proteasome Complex Nucleus Cytoplasm Dendrite Cdc48p-Npl4p-Ufd1p AAA ATPase Complex Neuronal Cell Body
	Molecular Function	Molecular_function	Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding ATPase Binding K6-linked Polyubiquitin Binding
	Biological Process	Biological_process	Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: BAG3 CALCOCO2 SFN STAM2 TAX1BP1 UBQLN1 UBXN1 WWP1 WWP2	15 interactors: ACVR1 BARD1 BMPR1B BRCA1 FAM189A2 HOMER2 PLA2G4A PLAA SMAD1 SMURF1 TGFBR1 TRIM39 UBE2I UBQLN1 VCP
Entrez ID		9413	51035
HPRD ID		16255	11266
Ensembl ID		ENSG00000135063	ENSG00000162191
Uniprot IDs		Q15884 Q8WU02	Q04323
PDB IDs
Enriched GO Terms of Interacting Partners?		Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Viral Entry Into Host Cell Entry Into Host Cell Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Epidermal Cell Division Protein Catabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Viral Life Cycle Regulation Of Protein Ubiquitination Cellular Macromolecule Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Keratinocyte Development Negative Regulation Of Keratinocyte Proliferation Apoptotic Process Negative Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Protein Export From Nucleus Regulation Of Metabolic Process Negative Regulation Of Striated Muscle Cell Apoptotic Process Cell Death Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Skin Barrier Apoptotic Signaling Pathway Negative Regulation Of Proteolysis Regulation Of Water Loss Via Skin Negative Regulation Of Protein Processing Positive Regulation Of Epidermal Cell Differentiation Regulation Of Keratinocyte Proliferation Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Processing Response To Stimulus Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Protein K63-linked Ubiquitination Regulation Of Protein Export From Nucleus Release Of Cytochrome C From Mitochondria	Regulation Of Apoptotic Process Regulation Of Cell Death BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Ossification Response To Stress Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Regulation Of Signal Transduction Positive Regulation Of Osteoblast Differentiation Signal Transduction By Phosphorylation Regulation Of Cartilage Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Signaling Positive Regulation Of Cell Death Positive Regulation Of Ossification Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Stimulus Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Protein Metabolic Process Pharyngeal System Development Regulation Of Osteoblast Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Postreplication Repair Inflammatory Response Activin Receptor Signaling Pathway Response To Organic Cyclic Compound Regulation Of Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Protein Polyubiquitination Negative Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Pattern Specification Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cartilage Development Positive Regulation Of Bone Mineralization Cell Cycle Process Positive Regulation Of Biomineral Tissue Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Tagcloud ?			adaptor antiviral dengue disrupts exhibits innate interferes mavs nile oligomerization potently repressing rig rlr rlrs sendai sensed signalosome stomatitis stringently strongest tlr3 tlr4 traf3 traf6 underscore vesicular west
Tagcloud (Difference) ?			adaptor antiviral dengue disrupts exhibits innate interferes mavs nile oligomerization potently repressing rig rlr rlrs sendai sensed signalosome stomatitis stringently strongest tlr3 tlr4 traf3 traf6 underscore vesicular west
Tagcloud (Intersection) ?