KIF3B and RAB4A

Number of citations of the paper that reports this interaction (PMID 12832475)
34

Data Source:
HPRD (in vivo, in vitro)

		KIF3B	RAB4A
Gene Name		kinesin family member 3B	RAB4A, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Plus-end Kinesin Complex Spindle Microtubule Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Intraciliary Transport Particle Extracellular Vesicular Exosome Primary Cilium Ciliary Tip	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding
	Biological Process	Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokinesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization
Pathways		Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System	Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS			Aging ( 22773346)
Protein-Protein Interactions		10 interactors: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L RAB4A	31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		9371	5867
HPRD ID		04781	01541
Ensembl ID		ENSG00000101350	ENSG00000168118
Uniprot IDs		B4DYF2 O15066	P20338
PDB IDs		3B6U	1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Plus-end-directed Vesicle Transport Along Microtubule Activation Of JNKK Activity Microtubule-based Movement Microtubule-based Process Smoothened Signaling Pathway Regulation Of Endocytosis Cellular Response To Stimulus Immune System Process Vesicle Transport Along Microtubule Positive Regulation Of Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Signal Transduction Antigen Processing And Presentation Intracellular Transport Organelle Transport Along Microtubule Signaling Visual Learning Activation Of MAPKK Activity Cell Communication Visual Behavior Positive Regulation Of JUN Kinase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Calcium-dependent Cell-cell Adhesion Opsin Transport Response To Stimulus Associative Learning Regulation Of JUN Kinase Activity JNK Cascade Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Blood Coagulation Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Hemostasis Establishment Of Localization In Cell Neuron Differentiation Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Process Stress-activated MAPK Cascade Positive Regulation Of Metabolic Process Heart Development Stress-activated Protein Kinase Signaling Cascade Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade	Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process
Tagcloud ?			abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Difference) ?			abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Intersection) ?