RAB4A and RAB11FIP1

Number of citations of the paper that reports this interaction (PMID 11786538)
37

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		RAB4A	RAB11FIP1
Gene Name		RAB4A, member RAS oncogene family	RAB11 family interacting protein 1 (class I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding	Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization	Protein Transport Regulated Secretory Pathway
Pathways		Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Aging ( 22773346)
Protein-Protein Interactions		31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	4 interactors: RAB11A RAB11B RAB25 RAB4A
Entrez ID		5867	80223
HPRD ID		01541	09787
Ensembl ID		ENSG00000168118	ENSG00000156675
Uniprot IDs		P20338	Q6WKZ4
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process	Rab Protein Signal Transduction Ras Protein Signal Transduction Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Regulation Of Vesicle-mediated Transport Pigmentation Small GTPase Mediated Signal Transduction Intracellular Protein Transport Establishment Of Vesicle Localization Vesicle Localization Establishment Of Organelle Localization Cellular Protein Localization Exocytosis Protein Transport Establishment Of Protein Localization Intracellular Transport Organelle Localization Secretion By Cell Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Positive Regulation Of Epithelial Cell Migration Secretion Cellular Localization Multivesicular Body Assembly Regulation Of Multivesicular Body Size Membrane Organization Regulation Of Epithelial Cell Migration Constitutive Secretory Pathway Multivesicular Body Organization Endosomal Transport Regulation Of Endosome Size Pseudopodium Organization Establishment Of Protein Localization To Membrane Exosomal Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle-mediated Transport Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cellular Response To Acidic PH Plasma Membrane To Endosome Transport Astral Microtubule Organization Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Protein Localization To Membrane Regulation Of Endocytic Recycling Receptor Recycling
Tagcloud ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	11q13 12p13 17q12 20q13 20q13co 20q13z 8p12 8q24 amplification amplifications amplified aurka bac centered fgfr1 frequencies histoclinical impacts loci mybl2 never nol1 organized probes recurrently spanning subregions tma znf217
Tagcloud (Difference) ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	11q13 12p13 17q12 20q13 20q13co 20q13z 8p12 8q24 amplification amplifications amplified aurka bac centered fgfr1 frequencies histoclinical impacts loci mybl2 never nol1 organized probes recurrently spanning subregions tma znf217
Tagcloud (Intersection) ?