KIF3B and KIFAP3

Number of citations of the paper that reports this interaction (PMID 9506951)
15

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		KIF3B	KIFAP3
Gene Name		kinesin family member 3B	kinesin-associated protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Plus-end Kinesin Complex Spindle Microtubule Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Intraciliary Transport Particle Extracellular Vesicular Exosome Primary Cilium Ciliary Tip	Condensed Nuclear Chromosome Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Axoneme Microtubule Cytoskeleton Kinesin II Complex Intraciliary Transport Particle Photoreceptor Connecting Cilium Ciliary Basal Body Extracellular Vesicular Exosome Primary Cilium Ciliary Tip Periciliary Membrane Compartment
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding	Protein Binding Kinesin Binding
	Biological Process	Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokinesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly	Protein Complex Assembly Organelle Organization Microtubule-based Process Microtubule-based Movement Signal Transduction Blood Coagulation Protein Localization Negative Regulation Of Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Negative Regulation Of Apoptotic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule
Pathways		Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System	Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 19451621)
Protein-Protein Interactions		10 interactors: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L RAB4A	18 interactors: APC AR DISC1 KIF3B MAP3K10 MAP3K11 MEST MINK1 NAA10 NCF2 NIPSNAP3A NUDT21 PEX19 RAP1GDS1 RBFOX1 RPGR SMC3 SRC
Entrez ID		9371	22920
HPRD ID		04781	03499
Ensembl ID		ENSG00000101350	ENSG00000075945
Uniprot IDs		B4DYF2 O15066	Q92845
PDB IDs		3B6U
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Plus-end-directed Vesicle Transport Along Microtubule Activation Of JNKK Activity Microtubule-based Movement Microtubule-based Process Smoothened Signaling Pathway Regulation Of Endocytosis Cellular Response To Stimulus Immune System Process Vesicle Transport Along Microtubule Positive Regulation Of Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Signal Transduction Antigen Processing And Presentation Intracellular Transport Organelle Transport Along Microtubule Signaling Visual Learning Activation Of MAPKK Activity Cell Communication Visual Behavior Positive Regulation Of JUN Kinase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Calcium-dependent Cell-cell Adhesion Opsin Transport Response To Stimulus Associative Learning Regulation Of JUN Kinase Activity JNK Cascade Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Blood Coagulation Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Hemostasis Establishment Of Localization In Cell Neuron Differentiation Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Process Stress-activated MAPK Cascade Positive Regulation Of Metabolic Process Heart Development Stress-activated Protein Kinase Signaling Cascade Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade	Organelle Organization Cytoskeleton Organization Microtubule-based Process Activation Of JNKK Activity Protein Autophosphorylation JNK Cascade Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Protein Complex Assembly Positive Regulation Of Cell Death Regulation Of MAPK Cascade Mitochondrial Calcium Ion Homeostasis Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Signal Transduction Positive Regulation Of Wnt Signaling Pathway Cellular Component Assembly Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Regulation Of JNK Cascade Positive Regulation Of MAPK Cascade Microtubule Cytoskeleton Organization Positive Regulation Of Phosphorylation Regulation Of Signal Transduction Regulation Of Stress-activated MAPK Cascade Regulation Of Apoptotic Process Activation Of JUN Kinase Activity Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Positive Regulation Of MAP Kinase Activity Mitotic Spindle Organization Regulation Of Cell Death MAPK Cascade Response To Progesterone Regulation Of Signaling Regulation Of Catalytic Activity Negative Regulation Of Integrin Biosynthetic Process Negative Regulation Of Lipid Binding Positive Regulation Of Neuron Apoptotic Process Activation Of Protein Kinase Activity Regulation Of Intracellular Signal Transduction Activation Of MAPKK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of Metabolic Process T Cell Differentiation In Thymus Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?			als amyotrophic angiogenin contributors decade deterioration determinant devastating directions discoveries extends extensively familial fifth fus incurable lifespan linking occurs progresses prolong riluzole sod1 sought sporadic therapeutics tls typically unc13a
Tagcloud (Difference) ?			als amyotrophic angiogenin contributors decade deterioration determinant devastating directions discoveries extends extensively familial fifth fus incurable lifespan linking occurs progresses prolong riluzole sod1 sought sporadic therapeutics tls typically unc13a
Tagcloud (Intersection) ?