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RAB4A and STX4
Number of citations of the paper that reports this interaction (PubMedID
11063739
)
0
Data Source:
HPRD
(in vitro, in vivo)
RAB4A
STX4
Description
RAB4A, member RAS oncogene family
syntaxin 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Membrane
Cytoplasmic Vesicle Membrane
Early Endosome Membrane
Vesicle
Insulin-responsive Compartment
Perinuclear Region Of Cytoplasm
Recycling Endosome
Recycling Endosome Membrane
Extracellular Exosome
Glutamatergic Synapse
Storage Vacuole
Extracellular Space
Cytoplasm
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Cell Surface
Endomembrane System
Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Stereocilium
Neuron Projection Membrane
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Cell Projection
Neuron Projection
Dendritic Spine
Lateral Loop
Synapse
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Postsynapse
Glutamatergic Synapse
Molecular Function
Nucleotide Binding
GTPase Activity
G Protein Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
Metal Ion Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
Biological Process
Small GTPase-mediated Signal Transduction
Protein Transport
Vesicle-mediated Transport
Antigen Processing And Presentation
Regulation Of Endocytosis
Rab Protein Signal Transduction
Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome
Vesicle-mediated Transport In Synapse
Positive Regulation Of Immunoglobulin Production
Neurotransmitter Transport
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Sensory Perception Of Sound
Positive Regulation Of Cell Population Proliferation
Vesicle-mediated Transport
Regulation Of Exocytosis
Positive Regulation Of Cell Migration
Protein Localization To Cell Surface
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Membrane Organization
Cellular Response To Type II Interferon
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Positive Regulation Of Protein Localization To Cell Surface
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Synthesis of PIPs at the plasma membrane
TBC/RABGAPs
RAB geranylgeranylation
MET receptor recycling
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Drugs
Diseases
GWAS
Aging (
22773346
)
Heel bone mineral density x serum urate levels interaction (
34046847
)
Leukoderma in response to rhododendrol (
32558222
)
Mean arterial pressure (alcohol consumption interaction) (
24376456
)
Mercury levels (
26025379
)
Response to antidepressants in depression (
27622933
)
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Interacting Genes
33 interacting genes:
ACTB
APBB3
CD2AP
CDK1
CHM
DYNC1LI1
DYNLL1
EXOC5
GARIN6
GDI2
GRIPAP1
HACE1
IDH3A
KCTD7
KIF3B
MAPK3
PIN1
PRKCI
PTTG1IP
RAB11FIP1
RAB7A
RABAC1
RABEP1
RABGAP1
RABGEF1
RBSN
RUFY1
SNCA
SOD2
STX4
TP53
VPS52
ZNF830
65 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP47
STX10
STX11
STX16
STX1A
STX1B
STX2
STX3
STX5
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP7
VAMP8
VAPB
VMA12
VTI1B
ZFPL1
Entrez ID
5867
6810
HPRD ID
01541
01722
Ensembl ID
ENSG00000168118
ENSG00000103496
Uniprot IDs
A0A087WYT5
P20338
B7Z425
Q12846
PDB IDs
1YU9
1Z0K
2BMD
2BME
Enriched GO Terms of Interacting Partners
?
Establishment Of Protein Localization
Intracellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Small GTPase Binding
Regulation Of Transport
Membrane Organization
Small GTPase-mediated Signal Transduction
Cellular Localization
Regulation Of Vesicle-mediated Transport
Regulation Of Protein Localization
Glutamatergic Synapse
Endosome
Cytosol
Organelle Organization
Intracellular Transport
Regulation Of Organelle Organization
Establishment Of Localization In Cell
Protein Targeting
Intracellular Signaling Cassette
Regulation Of Cellular Component Organization
Regulation Of Norepinephrine Uptake
Endosomal Transport
Regulation Of Secretion By Cell
Cytoplasm
Transporter Regulator Activity
Membrane Fusion
Regulation Of Protein Localization To Cell Periphery
Intracellular Signal Transduction
Regulation Of Protein Transport
Positive Regulation Of Protein Localization
Positive Regulation Of Transport
Regulation Of Secretion
Positive Regulation Of Secretion By Cell
Regulation Of Synaptic Vesicle Recycling
Positive Regulation Of Secretion
Retrograde Transport, Endosome To Golgi
Early Endosome Membrane
Exocytosis
Secretion
Post-Golgi Vesicle-mediated Transport
Negative Regulation Of Exocytosis
Regulation Of Cellular Localization
Nuclear DNA Replication
Localization Within Membrane
Regulation Of Establishment Of Protein Localization
Response To Oxidative Stress
Cellular Component Assembly
Regulation Of Protein Localization To Plasma Membrane
Tau Protein Binding
SNAP Receptor Activity
SNARE Complex
Membrane Fusion
Syntaxin Binding
Vesicle Fusion
Organelle Membrane Fusion
Organelle Fusion
Vesicle-mediated Transport
Membrane Organization
SNARE Binding
Vesicle Organization
Exocytosis
Organelle Localization By Membrane Tethering
Establishment Of Localization In Cell
Membrane Docking
Secretion By Cell
Vesicle Docking
Protein Transport
Secretion
Establishment Of Protein Localization
Vesicle-mediated Transport In Synapse
Golgi Vesicle Transport
Cellular Localization
Intracellular Protein Localization
Intracellular Transport
Organelle Localization
Regulation Of Vesicle-mediated Transport
Endomembrane System
Calcium-ion Regulated Exocytosis
SNARE Complex Assembly
Membrane
Regulated Exocytosis
Regulation Of Exocytosis
Syntaxin-1 Binding
Synaptic Vesicle Exocytosis
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Intracellular Protein Transport
Vesicle Fusion To Plasma Membrane
Regulation Of Secretion By Cell
Synaptic Vesicle Membrane
Regulation Of Secretion
Synaptic Vesicle Membrane Organization
Signal Release
Regulation Of Transport
Regulation Of Regulated Secretory Pathway
Synaptic Vesicle
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Vesicle Docking Involved In Exocytosis
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Post-Golgi Vesicle-mediated Transport
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