RAB4A and RBSN

Number of citations of the paper that reports this interaction (PMID 11788822)
75

Data Source:
HPRD (in vivo, in vitro)

		RAB4A	RBSN
Gene Name		RAB4A, member RAS oncogene family	rabenosyn, RAB effector
Image
Gene Ontology Annotations	Cellular Component	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Endosome Plasma Membrane Endosome Membrane Cytoplasmic Side Of Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding	Protein Binding Zinc Ion Binding Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization	Vacuole Inheritance Golgi To Endosome Transport Golgi To Vacuole Transport Endocytosis Blood Coagulation Protein Transport Endosomal Transport Endosomal Vesicle Fusion Late Endosome To Vacuole Transport
Pathways		Translocation of GLUT4 to the plasma membrane	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Aging ( 22773346)
Protein-Protein Interactions		31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	13 interactors: DISC1 DTNBP1 EHD1 EHD2 EHD3 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		5867	64145
HPRD ID		01541	15732
Ensembl ID		ENSG00000168118	ENSG00000131381
Uniprot IDs		P20338	Q9H1K0
PDB IDs		1YU9 1Z0K 2BMD 2BME	1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?		Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process	Rab Protein Signal Transduction Cellular Protein Localization Intracellular Protein Transport Intracellular Transport Ras Protein Signal Transduction Cellular Localization Protein Localization Establishment Of Localization In Cell Protein Transport Endocytic Recycling Establishment Of Protein Localization Endosomal Transport Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Response To Wounding Positive Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Vesicle-mediated Transport Positive Regulation Of Myotube Differentiation Positive Regulation Of Endocytic Recycling Regulation Of Vesicle-mediated Transport Response To Stimulus Intracellular Signal Transduction Transport Regulation Of Endocytic Recycling Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Regulation Of Cellular Component Organization Positive Regulation Of Transport Membrane Organization Regulation Of Muscle Cell Differentiation Endomembrane System Organization Regulation Of Endocytosis Regulation Of Cellular Localization Protein Targeting To Plasma Membrane Positive Regulation Of Intracellular Transport Endocytosis Protein Homooligomerization P38MAPK Cascade Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Neurotransmitter Secretion Signaling Cell Communication
Tagcloud ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Difference) ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Intersection) ?