RAB4A and VPS52

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RAB4A	VPS52
Gene Name		RAB4A, member RAS oncogene family	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding	Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways		Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Aging ( 22773346)
Protein-Protein Interactions		31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		5867	6293
HPRD ID		01541	09142
Ensembl ID		ENSG00000168118	ENSG00000223501
Uniprot IDs		P20338	B4DNI9 Q8N1B4
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?