KIF3B and MAP3K11

Number of citations of the paper that reports this interaction (PMID 9427749)
54

Data Source:
BioGRID (two hybrid)

		KIF3B	MAP3K11
Gene Name		kinesin family member 3B	mitogen-activated protein kinase kinase kinase 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Plus-end Kinesin Complex Spindle Microtubule Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Intraciliary Transport Particle Extracellular Vesicular Exosome Primary Cilium Ciliary Tip	Cytoplasm Centrosome Microtubule Membrane
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Homodimerization Activity Rac GTPase Binding
	Biological Process	Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokinesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly	Activation Of MAPK Activity Protein Phosphorylation Microtubule-based Process JNK Cascade Activation Of JNKK Activity Activation Of JUN Kinase Activity Cell Death Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of JNK Cascade Protein Autophosphorylation
Pathways		Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L RAB4A	27 interactors: AKT1 APP CDC42 CHUK CLEC4G COPS5 EPS8 IKBKB KIF17 KIF3A KIF3B KIFAP3 MAP2K4 MAP2K7 MAP3K12 MAP4K1 MAP4K2 MAPK8IP1 MAPK8IP2 MAPK8IP3 PIN1 RAC1 RHOG SH3RF1 STUB1 TRAF6 UBC
Entrez ID		9371	4296
HPRD ID		04781	02502
Ensembl ID		ENSG00000101350	ENSG00000173327
Uniprot IDs		B4DYF2 O15066	Q16584
PDB IDs		3B6U
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Plus-end-directed Vesicle Transport Along Microtubule Activation Of JNKK Activity Microtubule-based Movement Microtubule-based Process Smoothened Signaling Pathway Regulation Of Endocytosis Cellular Response To Stimulus Immune System Process Vesicle Transport Along Microtubule Positive Regulation Of Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Signal Transduction Antigen Processing And Presentation Intracellular Transport Organelle Transport Along Microtubule Signaling Visual Learning Activation Of MAPKK Activity Cell Communication Visual Behavior Positive Regulation Of JUN Kinase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Calcium-dependent Cell-cell Adhesion Opsin Transport Response To Stimulus Associative Learning Regulation Of JUN Kinase Activity JNK Cascade Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Blood Coagulation Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Hemostasis Establishment Of Localization In Cell Neuron Differentiation Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Process Stress-activated MAPK Cascade Positive Regulation Of Metabolic Process Heart Development Stress-activated Protein Kinase Signaling Cascade Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade	Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade JNK Cascade Regulation Of MAPK Cascade Regulation Of Signal Transduction Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Transferase Activity Regulation Of Intracellular Signal Transduction Regulation Of Signaling Regulation Of Phosphorylation Response To Stress Regulation Of Phosphorus Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Kinase Activity MAPK Cascade Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Regulation Of JUN Kinase Activity Fc Receptor Signaling Pathway Innate Immune Response Positive Regulation Of MAPK Cascade Signal Transduction Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Metabolic Process Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Protein Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Immune System Process Toll-like Receptor 2 Signaling Pathway Positive Regulation Of JNK Cascade Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?			acceleration activate agar besides carcinogenesis cdk2 colony crkl cycle cycling1 facilitate g1 htert mb mda methylate methyltransferase mynd oncogenes phenotypes pik3cb riz set smyd3 soft stat1 transduction transformed wnt10b
Tagcloud (Difference) ?			acceleration activate agar besides carcinogenesis cdk2 colony crkl cycle cycling1 facilitate g1 htert mb mda methylate methyltransferase mynd oncogenes phenotypes pik3cb riz set smyd3 soft stat1 transduction transformed wnt10b
Tagcloud (Intersection) ?