KIF3B and MAP3K10

Number of citations of the paper that reports this interaction (PMID 9427749)
54

Data Source:
HPRD (in vitro, two hybrid)

		KIF3B	MAP3K10
Gene Name		kinesin family member 3B	mitogen-activated protein kinase kinase kinase 10
Image
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Plus-end Kinesin Complex Spindle Microtubule Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Intraciliary Transport Particle Extracellular Vesicular Exosome Primary Cilium Ciliary Tip	Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding	Transcription Corepressor Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity ATP Binding Protein Homodimerization Activity BHLH Transcription Factor Binding
	Biological Process	Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokinesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly	Apoptotic Process Signal Transduction Smoothened Signaling Pathway JNK Cascade Activation Of JNKK Activity Activation Of JUN Kinase Activity Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of JUN Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Protein Autophosphorylation
Pathways		Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L RAB4A	30 interactors: ABL2 CDC42 CEACAM1 CLTC CNKSR1 COPS2 DLG4 DNM1 DNM1L GARS HGS HTT KIAA1804 KIF17 KIF3A KIF3B KIFAP3 MAP2K4 MAPK1 MAPK14 MAPK8IP1 MAPK8IP2 MAPK9 NEUROD1 PHB RAC1 RACGAP1 SH3RF1 TUBB YWHAE
Entrez ID		9371	4294
HPRD ID		04781	02533
Ensembl ID		ENSG00000101350	ENSG00000130758
Uniprot IDs		B4DYF2 O15066	Q02779
PDB IDs		3B6U	2RF0
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Plus-end-directed Vesicle Transport Along Microtubule Activation Of JNKK Activity Microtubule-based Movement Microtubule-based Process Smoothened Signaling Pathway Regulation Of Endocytosis Cellular Response To Stimulus Immune System Process Vesicle Transport Along Microtubule Positive Regulation Of Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Signal Transduction Antigen Processing And Presentation Intracellular Transport Organelle Transport Along Microtubule Signaling Visual Learning Activation Of MAPKK Activity Cell Communication Visual Behavior Positive Regulation Of JUN Kinase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Calcium-dependent Cell-cell Adhesion Opsin Transport Response To Stimulus Associative Learning Regulation Of JUN Kinase Activity JNK Cascade Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Blood Coagulation Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Hemostasis Establishment Of Localization In Cell Neuron Differentiation Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Process Stress-activated MAPK Cascade Positive Regulation Of Metabolic Process Heart Development Stress-activated Protein Kinase Signaling Cascade Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade	Regulation Of Intracellular Signal Transduction Movement Of Cell Or Subcellular Component Signal Transduction Regulation Of Signal Transduction Regulation Of Stress-activated MAPK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Signaling Regulation Of Signaling Cell Communication Neurogenesis Cell Differentiation Regulation Of JNK Cascade Generation Of Neurons Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of MAPK Cascade Organelle Organization Cellular Localization Cellular Response To Stimulus Neuron Differentiation Response To Stimulus Regulation Of Apoptotic Process Developmental Process Organelle Transport Along Microtubule Regulation Of Phosphorus Metabolic Process MAPK Cascade Response To Stress Intracellular Transport Regulation Of Cell Death Protein Localization Nervous System Development Cytoskeleton-dependent Intracellular Transport Regulation Of Body Fluid Levels Positive Regulation Of Intracellular Signal Transduction Plus-end-directed Vesicle Transport Along Microtubule Wound Healing Regulation Of Catalytic Activity Signal Transduction By Phosphorylation Membrane Organization Transport JNK Cascade Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Microtubule-based Movement Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule Response To Wounding
Tagcloud ?			artp calculating chief convergence dusp2 hrgg il2ra il6 il8ra il8rb infgr1 irf2 merits mmp1 nfkb1a nos2a partp pik3ca polygenic pttrnd raf1 rectal runx3 sepx1 smad3 soc strongest truncation tyk2
Tagcloud (Difference) ?			artp calculating chief convergence dusp2 hrgg il2ra il6 il8ra il8rb infgr1 irf2 merits mmp1 nfkb1a nos2a partp pik3ca polygenic pttrnd raf1 rectal runx3 sepx1 smad3 soc strongest truncation tyk2
Tagcloud (Intersection) ?