RAB4A and ZNF830

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RAB4A	ZNF830
Description		RAB4A, member RAS oncogene family	zinc finger protein 830
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nuclear Speck
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Small GTPase-mediated Signal Transduction Protein Transport Vesicle-mediated Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Vesicle-mediated Transport In Synapse	Mitotic Cell Cycle Ovarian Follicle Development Preantral Ovarian Follicle Growth Blastocyst Growth RNA Processing MRNA Processing RNA Splicing Nuclear DNA Replication Mitotic DNA Replication Checkpoint Signaling Negative Regulation Of Apoptotic Process Mitotic DNA Damage Checkpoint Signaling Chromosome Organization Cell Division Intestinal Epithelial Structure Maintenance
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Aging ( 22773346) Heel bone mineral density x serum urate levels interaction ( 34046847) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)	Night sleep phenotypes ( 27126917)
Interacting Genes		33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GARIN6 GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABGAP1 RABGEF1 RBSN RUFY1 SNCA SOD2 STX4 TP53 VPS52 ZNF830	11 interacting genes: CLK1 FRA10AC1 ILF3 LARP4 PCBP1 PCM1 PPIL2 PRPF8 RAB4A SESTD1 THOC5
Entrez ID		5867	91603
HPRD ID		01541	14469
Ensembl ID		ENSG00000168118	ENSG00000198783
Uniprot IDs		A0A087WYT5 P20338	Q96NB3
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Small GTPase Binding Regulation Of Transport Membrane Organization Small GTPase-mediated Signal Transduction Cellular Localization Regulation Of Vesicle-mediated Transport Regulation Of Protein Localization Glutamatergic Synapse Endosome Cytosol Organelle Organization Intracellular Transport Regulation Of Organelle Organization Establishment Of Localization In Cell Protein Targeting Intracellular Signaling Cassette Regulation Of Cellular Component Organization Regulation Of Norepinephrine Uptake Endosomal Transport Regulation Of Secretion By Cell Cytoplasm Transporter Regulator Activity Membrane Fusion Regulation Of Protein Localization To Cell Periphery Intracellular Signal Transduction Regulation Of Protein Transport Positive Regulation Of Protein Localization Positive Regulation Of Transport Regulation Of Secretion Positive Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Secretion Retrograde Transport, Endosome To Golgi Early Endosome Membrane Exocytosis Secretion Post-Golgi Vesicle-mediated Transport Negative Regulation Of Exocytosis Regulation Of Cellular Localization Nuclear DNA Replication Localization Within Membrane Regulation Of Establishment Of Protein Localization Response To Oxidative Stress Cellular Component Assembly Regulation Of Protein Localization To Plasma Membrane Tau Protein Binding	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions
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