RAB4A and GDI2

Number of citations of the paper that reports this interaction (PMID 10512627)
11

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RAB4A	GDI2
Gene Name		RAB4A, member RAS oncogene family	GDP dissociation inhibitor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Cytosol Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding	Rab GDP-dissociation Inhibitor Activity Rab GTPase Activator Activity Protein Binding Small GTPase Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of Rab GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Translocation of GLUT4 to the plasma membrane	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Aging ( 22773346)	Osteosarcoma ( 23727862)
Protein-Protein Interactions		31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	7 interactors: GLRA2 RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A
Entrez ID		5867	2665
HPRD ID		01541	02863
Ensembl ID		ENSG00000168118	ENSG00000057608
Uniprot IDs		P20338	E7EU23 P50395 Q6IAT1
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process	Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endosome Size Cellular Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Neuronal Synaptic Plasticity Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Regulation Of Exocytosis Regulation Of Synaptic Plasticity Transport Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Signal Transduction Signaling Cell Communication Regulation Of Synaptic Transmission Establishment Of Organelle Localization Cellular Response To Stimulus Positive Regulation Of Exocytosis Organelle Localization Endomembrane System Organization Multivesicular Body Assembly Regulation Of Multivesicular Body Size Vesicle-mediated Transport Synaptic Vesicle Transport Multivesicular Body Organization Response To Stimulus Regulation Of Secretion Protein Localization To Plasma Membrane Golgi Vesicle Fusion To Target Membrane Receptor Internalization Involved In Canonical Wnt Signaling Pathway Mitotic Cell Cycle Exosomal Secretion Regulation Of Endocytosis Membrane Organization Plasma Membrane Organization Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Cellular Localization Positive Regulation Of Secretion
Tagcloud ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	actb aldoa aldr catb catd catg co3 conceptus cst6 gd1b gda gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Difference) ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	actb aldoa aldr catb catd catg co3 conceptus cst6 gd1b gda gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn
Tagcloud (Intersection) ?