RAB4A and RABGAP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RAB4A	RABGAP1
Gene Name		RAB4A, member RAS oncogene family	RAB GTPase activating protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Centrosome Cytosol Microtubule Associated Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding	DNA Binding GTPase Activator Activity Rab GTPase Activator Activity Protein Binding Tubulin Binding Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization	Cell Cycle Positive Regulation Of Rab GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Aging ( 22773346)
Protein-Protein Interactions		31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	9 interactors: CARM1 DISC1 GABARAPL1 MAP1LC3A RAB4A RAB6A RAB6B SENP1 SENP5
Entrez ID		5867	23637
HPRD ID		01541	06575
Ensembl ID		ENSG00000168118	ENSG00000011454
Uniprot IDs		P20338	Q9Y3P9
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process	Rab Protein Signal Transduction Nucleophagy Protein Sumoylation Mitochondrion Degradation Ras Protein Signal Transduction Retrograde Vesicle-mediated Transport, Golgi To ER Cell Communication Organelle Disassembly Autophagic Vacuole Assembly Intra-Golgi Vesicle-mediated Transport Macroautophagy Cellular Response To Stimulus Peptidyl-amino Acid Modification Retrograde Transport, Endosome To Golgi Histone H3-R17 Methylation Vacuole Organization Histone H3-R2 Methylation Cellular Protein Localization Membrane Fusion Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Cellular Response To Starvation Response To Stimulus Small GTPase Mediated Signal Transduction Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Protein Desumoylation Regulation Of Definitive Erythrocyte Differentiation Autophagy Protein Methylation Cellular Response To Nutrient Levels Response To Starvation Post-translational Protein Modification Endosomal Transport Cellular Response To Extracellular Stimulus Membrane Organization Intracellular Signal Transduction Protein Localization Early Endosome To Golgi Transport Peptidyl-lysine Modification Intracellular Protein Transport Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Golgi Vesicle Transport Antigen Processing And Presentation Signal Transduction Positive Regulation Of Proteolysis Peptidyl-arginine N-methylation Cellular Response To Nitrogen Starvation Mitochondrial Calcium Ion Homeostasis Intracellular Estrogen Receptor Signaling Pathway Signaling
Tagcloud ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera	akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?