MAGI1 and ATN1

Number of citations of the paper that reports this interaction (PMID 9647693)
24

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		MAGI1	ATN1
Gene Name		membrane associated guanylate kinase, WW and PDZ domain containing 1	atrophin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Tight Junction Cell Junction Cell Projection	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Protein Complex Scaffold Alpha-actinin Binding	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	Protein Complex Assembly Cell Adhesion Cell Surface Receptor Signaling Pathway Neuron Death	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways
Drugs
Diseases
GWAS		PR interval ( 23534349)
Protein-Protein Interactions		23 interactors: ACTN4 AMOT ASIC3 ATN1 BAI1 CLCN5 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		9223	1822
HPRD ID		04020	06311
Ensembl ID		ENSG00000151276	ENSG00000111676
Uniprot IDs		Q96QZ7	P54259 Q86V38
PDB IDs		2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU
Enriched GO Terms of Interacting Partners?		Locomotion Response To External Stimulus Nervous System Development Movement Of Cell Or Subcellular Component Chemotaxis Apoptotic Process Cell Morphogenesis Involved In Differentiation Programmed Cell Death Cell Death Death Axonogenesis Neuron Differentiation System Development Regulation Of Cellular Component Organization Generation Of Neurons Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neurogenesis Axon Guidance Neuron Projection Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Neuron Development Neurotrophin Signaling Pathway Multicellular Organismal Development Regulation Of Cellular Process Cell Morphogenesis Signaling Anatomical Structure Development Regulation Of Apoptotic Process Cell Communication Cellular Response To Stimulus Regulation Of Cell Death Neuron Projection Development Cell Projection Morphogenesis Signal Transduction Cell Part Morphogenesis Cellular Response To Growth Factor Stimulus Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Organelle Organization Positive Regulation Of Cellular Component Movement Response To Growth Factor Developmental Process Toll-like Receptor 5 Signaling Pathway Response To Stimulus Toll-like Receptor 10 Signaling Pathway Cell Development Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Central Nervous System Development Toll-like Receptor 2 Signaling Pathway	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?