ATN1 and CRIP2

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	CRIP2
Description		atrophin 1	cysteine rich protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Perinuclear Region Of Cytoplasm Anchoring Junction	Cell Cortex
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Killing Spermatogenesis Central Nervous System Development Determination Of Adult Lifespan Male Gonad Development Post-embryonic Development Cell Migration Maintenance Of Cell Polarity Response To Food Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Neuron Apoptotic Process	Positive Regulation Of Cell Population Proliferation Hemopoiesis
Pathways		Regulation of PTEN gene transcription
Drugs
Diseases		Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Refractive error ( 32231278)
Interacting Genes		126 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CHRD CPAP CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SAXO4 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 YAP1 ZMYND8 ZNF503 ZSWIM8	19 interacting genes: APP ATN1 ATP1B1 ATXN1 CDC42 ERBB2 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1
Entrez ID		1822	1397
HPRD ID		06311	03113
Ensembl ID		ENSG00000111676	ENSG00000182809
Uniprot IDs		P54259 Q86V38	P52943
PDB IDs			2CU8
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Developmental Process Extracellular Matrix Structural Constituent Positive Regulation Of Metabolic Process Regulation Of Gene Expression Calcium Ion Binding Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Transcription Corepressor Activity Regulation Of Protein Stability Elastic Fiber Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway System Development Apoptotic Process DNA-binding Transcription Factor Binding Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Programmed Cell Death Cell Death Histone H3 Acetyltransferase Activity Regulation Of Cell Population Proliferation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Projection Organization Signal Transduction Positive Regulation Of RNA Metabolic Process	Developmental Growth Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Neuron Projection Development Regulation Of Multicellular Organismal Process Developmental Cell Growth Cardiac Vascular Smooth Muscle Cell Differentiation Developmental Growth Involved In Morphogenesis Tube Morphogenesis NFAT Protein Binding Atrioventricular Node Development Cardiocyte Differentiation Muscle Tissue Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Cell Fate Commitment Vascular Associated Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Negative Regulation Of Transcription By RNA Polymerase II Atrioventricular Canal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Animal Organ Development Regulation Of Multicellular Organismal Development Intestinal Epithelial Cell Differentiation Forebrain Development System Development Wound Healing Regulation Of MiRNA Transcription Regulation Of Developmental Process Developmental Process System Process Protein Kinase Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Muscle System Process Positive Regulation Of Growth Collateral Sprouting Associative Learning Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Biosynthetic Process
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