MAGI1 and ASIC3

Number of citations of the paper that reports this interaction (PMID 15317815)
21

Data Source:
HPRD (in vivo, two hybrid)

		MAGI1	ASIC3
Gene Name		membrane associated guanylate kinase, WW and PDZ domain containing 1	acid sensing (proton gated) ion channel 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Tight Junction Cell Junction Cell Projection	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Protein Complex Scaffold Alpha-actinin Binding	Cation Channel Activity Sodium Channel Activity Ligand-gated Sodium Channel Activity PDZ Domain Binding Enterobactin Transporter Activity
	Biological Process	Protein Complex Assembly Cell Adhesion Cell Surface Receptor Signaling Pathway Neuron Death	Transport Signal Transduction Sensory Perception Response To Heat Response To Acidic PH Ion Transmembrane Transport Sodium Ion Transmembrane Transport Enterobactin Transport Sensory Perception Of Sour Taste Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Transmembrane Transport Cation Transmembrane Transport
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		PR interval ( 23534349)
Protein-Protein Interactions		23 interactors: ACTN4 AMOT ASIC3 ATN1 BAI1 CLCN5 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2	9 interactors: ASIC2 CSNK2A1 DLG4 GOPC INADL LIN7B MAGI1 PRKACA STOM
Entrez ID		9223	9311
HPRD ID		04020	10626
Ensembl ID		ENSG00000151276	ENSG00000213199
Uniprot IDs		Q96QZ7	Q9UHC3
PDB IDs		2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU
Enriched GO Terms of Interacting Partners?		Locomotion Response To External Stimulus Nervous System Development Movement Of Cell Or Subcellular Component Chemotaxis Apoptotic Process Cell Morphogenesis Involved In Differentiation Programmed Cell Death Cell Death Death Axonogenesis Neuron Differentiation System Development Regulation Of Cellular Component Organization Generation Of Neurons Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neurogenesis Axon Guidance Neuron Projection Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Neuron Development Neurotrophin Signaling Pathway Multicellular Organismal Development Regulation Of Cellular Process Cell Morphogenesis Signaling Anatomical Structure Development Regulation Of Apoptotic Process Cell Communication Cellular Response To Stimulus Regulation Of Cell Death Neuron Projection Development Cell Projection Morphogenesis Signal Transduction Cell Part Morphogenesis Cellular Response To Growth Factor Stimulus Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Organelle Organization Positive Regulation Of Cellular Component Movement Response To Growth Factor Developmental Process Toll-like Receptor 5 Signaling Pathway Response To Stimulus Toll-like Receptor 10 Signaling Pathway Cell Development Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Central Nervous System Development Toll-like Receptor 2 Signaling Pathway	Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Maintenance Of Apical/basal Cell Polarity Regulation Of Cation Channel Activity Maintenance Of Cell Polarity Regulation Of Ion Transmembrane Transport Cellular Component Assembly Protein Localization To Synapse Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Golgi To Plasma Membrane Transport Cell-cell Signaling Regulation Of Sodium Ion Transport Regulation Of Cellular Component Organization Negative Regulation Of Transport Protein Complex Assembly Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Positive Regulation Of Dense Core Granule Biogenesis Cytoplasmic Sequestering Of CFTR Protein Regulation Of Acid-sensing Ion Channel Activity Post-Golgi Vesicle-mediated Transport Phototransduction Regulation Of Blood Coagulation Detection Of Light Stimulus Histone H3-T6 Phosphorylation Cell-cell Junction Assembly Nucleus Organization Signaling Regulation Of Wound Healing Cell Communication Synaptic Transmission Chemotaxis Spermatid Development Spermatid Differentiation Negative Regulation Of MAPK Cascade Protein Localization To Basolateral Plasma Membrane Sensory Perception Of Sour Taste Detection Of Abiotic Stimulus Cytosolic Calcium Ion Homeostasis Establishment Or Maintenance Of Cell Polarity Regulation Of Behavior Positive Regulation Of Transport Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Grooming Behavior Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of ERK1 And ERK2 Cascade Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ion Transport
Tagcloud ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants	amiloride asic1 asic1a asic2a asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Difference) ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants	amiloride asic1 asic1a asic2a asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Intersection) ?