MAGI1 and IGSF5

Number of citations of the paper that reports this interaction (PMID 12773569)
30

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		MAGI1	IGSF5
Gene Name		membrane associated guanylate kinase, WW and PDZ domain containing 1	immunoglobulin superfamily, member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Tight Junction Cell Junction Cell Projection	Plasma Membrane Cell-cell Junction Tight Junction Cell Surface Integral Component Of Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Protein Complex Scaffold Alpha-actinin Binding	PDZ Domain Binding
	Biological Process	Protein Complex Assembly Cell Adhesion Cell Surface Receptor Signaling Pathway Neuron Death	Single Organismal Cell-cell Adhesion Regulation Of Neurogenesis
Pathways
Drugs
Diseases
GWAS		PR interval ( 23534349)	Coronary heart disease ( 21347282)
Protein-Protein Interactions		23 interactors: ACTN4 AMOT ASIC3 ATN1 BAI1 CLCN5 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2	3 interactors: LNX1 LNX2 MAGI1
Entrez ID		9223	150084
HPRD ID		04020	19125
Ensembl ID		ENSG00000151276	ENSG00000183067
Uniprot IDs		Q96QZ7	Q9NSI5
PDB IDs		2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU
Enriched GO Terms of Interacting Partners?		Locomotion Response To External Stimulus Nervous System Development Movement Of Cell Or Subcellular Component Chemotaxis Apoptotic Process Cell Morphogenesis Involved In Differentiation Programmed Cell Death Cell Death Death Axonogenesis Neuron Differentiation System Development Regulation Of Cellular Component Organization Generation Of Neurons Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neurogenesis Axon Guidance Neuron Projection Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Neuron Development Neurotrophin Signaling Pathway Multicellular Organismal Development Regulation Of Cellular Process Cell Morphogenesis Signaling Anatomical Structure Development Regulation Of Apoptotic Process Cell Communication Cellular Response To Stimulus Regulation Of Cell Death Neuron Projection Development Cell Projection Morphogenesis Signal Transduction Cell Part Morphogenesis Cellular Response To Growth Factor Stimulus Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Organelle Organization Positive Regulation Of Cellular Component Movement Response To Growth Factor Developmental Process Toll-like Receptor 5 Signaling Pathway Response To Stimulus Toll-like Receptor 10 Signaling Pathway Cell Development Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Central Nervous System Development Toll-like Receptor 2 Signaling Pathway	Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Oligomerization Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Sodium Ion Transport Negative Regulation Of ERK1 And ERK2 Cascade Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Neuron Death Regulation Of Sodium Ion Transport
Tagcloud ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants
Tagcloud (Difference) ?		01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel clca2 complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 manifestations nodosum pcombined phenotypes replicated structuring variants
Tagcloud (Intersection) ?