ATN1 and PDCD6IP

Number of citations of the paper that reports this interaction (PMID 9647693)
24

Data Source:
HPRD (in vitro, two hybrid)

		ATN1	PDCD6IP
Gene Name		atrophin 1	programmed cell death 6 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Immunological Synapse Cytoplasm Microtubule Organizing Center Cytosol Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding	Protein Binding SH3 Domain Binding Proteinase Activated Receptor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Viral Life Cycle Viral Budding Via Host ESCRT Complex Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly
Pathways			HIV Life Cycle Budding and maturation of HIV virion Uptake and actions of bacterial toxins HIV Infection Uptake and function of anthrax toxins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	35 interactors: ARRDC1 ARRDC3 ATN1 CD2AP CEP55 CHMP4A CHMP4B CHMP4C CXCR1 EGFR F2R GRB2 HOXA1 ITSN1 ITSN2 KEAP1 MAPK6 PDCD6 PTK2B RAMP3 RNF11 SDCBP SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3RF1 SRC TAB1 TNIP2 TSG101 TTF2 VPS28 VPS37C YES1
Entrez ID		1822	10015
HPRD ID		06311	06425
Ensembl ID		ENSG00000111676	ENSG00000170248
Uniprot IDs		P54259 Q86V38	C5MQH7 Q8WUM4
PDB IDs			2OEV 2OEW 2OEX 2OJQ 2R02 2R03 2R05 2XS1 2XS8 2ZNE 3C3O 3C3Q 3C3R 3E1R 4JJY
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development	Virion Assembly Locomotion Endocytosis Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Cell Migration Cell Separation After Cytokinesis Membrane Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Chemotaxis Viral Budding Transport Regulation Of Signal Transduction Viral Life Cycle Regulation Of Cellular Process Establishment Of Protein Localization Endosomal Transport Viral Protein Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Viral Process Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Intracellular Signal Transduction Cell Projection Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Organelle Organization Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Positive Regulation Of Metabolic Process Intracellular Transport Neuron Development Anatomical Structure Development Apoptotic Process Cell Morphogenesis Involved In Differentiation
Tagcloud ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Difference) ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Intersection) ?