ATN1 and KRTAP9-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATN1	KRTAP9-3
Description		atrophin 1	keratin associated protein 9-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Perinuclear Region Of Cytoplasm Anchoring Junction	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Killing Spermatogenesis Central Nervous System Development Determination Of Adult Lifespan Male Gonad Development Post-embryonic Development Cell Migration Maintenance Of Cell Polarity Response To Food Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Neuron Apoptotic Process
Pathways		Regulation of PTEN gene transcription	Keratinization
Drugs
Diseases		Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Refractive error ( 32231278)
Interacting Genes		126 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CHRD CPAP CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SAXO4 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 YAP1 ZMYND8 ZNF503 ZSWIM8	135 interacting genes: ADAMTSL4 ALPP ANKS1A ATN1 CARD10 CATSPER1 CCER1 CELF5 CERCAM CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CRH CYSRT1 DCDC2 DMRT3 DOCK2 ECM1 FAM124B FBXO34 FBXW5 GET4 GLRX3 GNE HOXA1 HOXA9 INCA1 ITGB4 JOSD1 KLHL38 KLK8 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 MAPKBP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NPDC1 NR1D2 NR4A3 NTM NUFIP2 OTX1 PAX5 PAX6 PGAP6 PHLDA1 POU4F2 PRKAB2 PTPMT1 PVR RAMP3 RGS20 SH3GLB2 SHFL SLC13A5 SLC23A1 SLC25A18 SMCP SPMIP6 SPRY1 TFAP2D TOX3 TRIM42 TSPAN4 UNC119 VASN VGLL3 WNT11 YY1 ZDHHC1 ZNF414 ZNF439 ZNF440 ZNF497 ZNF575
Entrez ID		1822	83900
HPRD ID		06311	13950
Ensembl ID		ENSG00000111676	ENSG00000204873
Uniprot IDs		P54259 Q86V38	Q9BYQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Developmental Process Extracellular Matrix Structural Constituent Positive Regulation Of Metabolic Process Regulation Of Gene Expression Calcium Ion Binding Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Transcription Corepressor Activity Regulation Of Protein Stability Elastic Fiber Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway System Development Apoptotic Process DNA-binding Transcription Factor Binding Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Programmed Cell Death Cell Death Histone H3 Acetyltransferase Activity Regulation Of Cell Population Proliferation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Projection Organization Signal Transduction Positive Regulation Of RNA Metabolic Process	Intermediate Filament Keratin Filament Keratinization Epidermis Development Protein Binding Tissue Development Hair Cycle
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