ATN1 and CACNB1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	CACNB1
Gene Name		atrophin 1	calcium channel, voltage-dependent, beta 1 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Voltage-gated Calcium Channel Complex Sarcoplasmic Reticulum T-tubule
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding	Voltage-gated Calcium Channel Activity High Voltage-gated Calcium Channel Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process	Protein Targeting To Membrane Transport Synaptic Transmission Axon Guidance Neuromuscular Junction Development Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity
Pathways			NCAM1 interactions Axon guidance NCAM signaling for neurite out-growth Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Transmission across Chemical Synapses
Drugs			Ibutilide Nimodipine Magnesium Sulfate Verapamil Mibefradil Dronedarone
Diseases
GWAS
Protein-Protein Interactions		93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	7 interactors: APP ATN1 CACNA1A DYNLL1 NEDD4L REM1 SRPK1
Entrez ID		1822	782
HPRD ID		06311	11743
Ensembl ID		ENSG00000111676	ENSG00000067191
Uniprot IDs		P54259 Q86V38	Q02641
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development	Central Nervous System Development Negative Regulation Of Cellular Metabolic Process Neural Nucleus Development Neuron Apoptotic Process Cell Death Death Neuron Death Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Neuromuscular Process Controlling Balance Cellular Ion Homeostasis Synapse Assembly Metal Ion Homeostasis Action Potential Cerebellar Molecular Layer Development Cellular Chemical Homeostasis Viral Process Ion Homeostasis Adult Locomotory Behavior Vestibular Nucleus Development Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Neuromuscular Process Signal Transduction Dendrite Development RNA Metabolic Process Cellular Homeostasis Cell Growth Collateral Sprouting In Absence Of Injury Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Nitrogen Compound Metabolic Process Signaling Adult Behavior Gene Expression Synapse Organization Brain Development Gamma-aminobutyric Acid Secretion Cell Communication Regulation Of Protein Localization Sexual Reproduction Head Development Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Acetylcholine Secretion, Neurotransmission Chemical Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Rhythmic Synaptic Transmission Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Tagcloud ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?