LACRT and VTN

Number of citations of the paper that reports this interaction (PubMedID 11419941)
0

Data Source:
HPRD (in vitro)

		LACRT	VTN
Description		lacritin	vitronectin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule	Extracellular Region Basement Membrane Extracellular Space Endoplasmic Reticulum Golgi Lumen Symbiont-containing Vacuole Extracellular Matrix Rough Endoplasmic Reticulum Lumen Extracellular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle Protein Complex Involved In Cell-matrix Adhesion Peptidase Inhibitor Complex
	Molecular Function	Protein Binding Collagen Binding Growth Factor Activity Laminin-1 Binding	Scavenger Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Collagen Binding Heparin Binding Polysaccharide Binding Identical Protein Binding Extracellular Matrix Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Epithelial Structure Maintenance Positive Regulation Of Macroautophagy Calcium-mediated Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Calcineurin-NFAT Signaling Cascade Protein Localization To Golgi Apparatus Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Secretion Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Tear Secretion Positive Regulation Of Calcineurin-NFAT Signaling Cascade	Immune Response Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Smooth Muscle Cell Migration Vesicle-mediated Transport Cell Migration Cell Differentiation Regulation Of Cell Adhesion Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Negative Regulation Of Proteolysis Positive Regulation Of Receptor-mediated Endocytosis Oligodendrocyte Differentiation Protein Polymerization Negative Regulation Of Fibrinolysis Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing Liver Regeneration Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways			Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans ECM proteoglycans Regulation of Complement cascade Developmental Lineage of Pancreatic Ductal Cells
Drugs			Abciximab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 32154731 33339817) Osteoprotegerin levels ( 25080503)
Interacting Genes		6 interacting genes: APP FN1 NID1 SDC1 TGM2 VTN	50 interacting genes: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 DLG2 DLG3 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA2B ITGA5 ITGA8 ITGAV ITGB3 ITGB6 ITGB8 KNG1 LACRT LNX2 PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 SNTG1 TGFB1 TGFB2 TNFRSF11B UBQLN2 VEGFA
Entrez ID		90070	7448
HPRD ID		06302	01902
Ensembl ID		ENSG00000135413	ENSG00000109072
Uniprot IDs		Q9GZZ8	D9ZGG2 P04004
PDB IDs			1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2 4K24 6O5E 7RJ9
Enriched GO Terms of Interacting Partners?		Peptidase Activator Activity Golgi Lumen Extracellular Region Extracellular Exosome Collagen Binding Extracellular Matrix Basement Membrane Cell-matrix Adhesion Protein Complex Involved In Cell-matrix Adhesion Extracellular Matrix Structural Constituent Positive Regulation Of Cell-substrate Adhesion Proteoglycan Binding Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Cell Adhesion Integrin Binding Cellular Response To Catecholamine Stimulus Regulation Of Vesicle-mediated Transport Heparin Binding Cell-substrate Adhesion Response To Catecholamine Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell-substrate Adhesion Extracellular Matrix Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cell Adhesion Endodermal Cell Differentiation Cell Adhesion Positive Regulation Of Cell Differentiation Regulation Of Endocytosis Positive Regulation Of Receptor-mediated Endocytosis Platelet Alpha Granule Lumen Positive Regulation Of Cellular Component Organization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endocytosis Vesicle-mediated Transport Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptide Serotonyltransferase Activity	Platelet Alpha Granule Lumen Integrin Complex Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Programmed Cell Death Integrin Binding Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cell-matrix Adhesion Regulation Of Apoptotic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Locomotion Cell-cell Adhesion Positive Regulation Of Vasculature Development Cell Surface Regulation Of Vesicle-mediated Transport Regulation Of Cell Communication Regulation Of Signaling Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Epithelial Tube Formation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Signaling Receptor Binding Negative Regulation Of Multicellular Organismal Process Cell Adhesion Growth Factor Activity Angiogenesis Cell-substrate Adhesion Integrin-mediated Signaling Pathway Cell Adhesion Mediated By Integrin Regulation Of Endocytosis Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Programmed Cell Death Alphav-beta3 Integrin-PKCalpha Complex Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of Protein Localization Regulation Of Vasculature Development Regulation Of Transport Positive Regulation Of Angiogenesis Positive Regulation Of Protein Localization Regulation Of Morphogenesis Of An Epithelium Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of MAPK Cascade Regulation Of Cell Migration Positive Regulation Of Morphogenesis Of An Epithelium
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?