FOXH1 and DRAP1

Number of citations of the paper that reports this interaction (PMID 12471260)
13

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vivo, in vitro)

		FOXH1	DRAP1
Gene Name		forkhead box H1	DR1-associated protein 1 (negative cofactor 2 alpha)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Activin Responsive Factor Complex	Nucleus
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Cofactor Activity RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Enhancer Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding SMAD Binding Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Heart Looping Secondary Heart Field Specification Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Androgen Receptor Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways		Signaling by Activin Signaling by NODAL	Signaling by Activin Signaling by NODAL
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: DRAP1 FOXG1 NKX2-5 SMAD2 SMAD3 SMAD4	22 interactors: APP ARHGEF10L CDKN2C DNAJB11 DR1 FEZ1 FEZ2 FOXH1 GTF2B LMO2 NCK2 NFYB PIK3R3 POLE3 SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1
Entrez ID		8928	10589
HPRD ID		04689	03796
Ensembl ID		ENSG00000160973	ENSG00000175550
Uniprot IDs		O75593	Q14919
PDB IDs			1JFI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Stem Cell Differentiation SMAD Protein Complex Assembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Mesenchyme Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Endoderm Development Primary MiRNA Processing Embryonic Pattern Specification Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Tube Morphogenesis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Pattern Specification Process Mesonephros Development Growth Positive Regulation Of Cell Development Heart Development Transforming Growth Factor Beta Receptor Signaling Pathway Mesoderm Development Kidney Epithelium Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Nodal Signaling Pathway RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Embryonic Morphogenesis Embryonic Foregut Morphogenesis Tissue Morphogenesis Response To Transforming Growth Factor Beta Foregut Morphogenesis Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Paraxial Mesoderm Development Gene Expression Tube Development Production Of MiRNAs Involved In Gene Silencing By MiRNA	Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process DNA-templated Transcription, Elongation Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription, DNA-templated Gene Expression Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Histone H3 Acetylation Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cellular Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Viral Process Histone Acetylation Regulation Of Receptor Activity Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Internal Protein Amino Acid Acetylation Response To Organic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Acetylation Negative Regulation Of Transcription, DNA-templated Regulation Of Epidermal Growth Factor-activated Receptor Activity
Tagcloud ?		alphav antiangiogenic beta3 bioactivities dextran dishes epas1 epc epcs erg exponentially floating fosl1 gata1 hey1 hhex hif1a icam1 id1 medicines mmp9 nfkb1 r1 smad1 tie2 transductions vasculogenesis vcam1 ve
Tagcloud (Difference) ?		alphav antiangiogenic beta3 bioactivities dextran dishes epas1 epc epcs erg exponentially floating fosl1 gata1 hey1 hhex hif1a icam1 id1 medicines mmp9 nfkb1 r1 smad1 tie2 transductions vasculogenesis vcam1 ve
Tagcloud (Intersection) ?