FOXH1 and MAGED1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FOXH1	MAGED1
Description		forkhead box H1	MAGE family member D1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Activin Responsive Factor Complex	Chromatin Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding SMAD Binding Nuclear Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding DNA-binding Transcription Factor Binding	Transcription Coactivator Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Heart Looping Secondary Heart Field Specification Determination Of Left/right Asymmetry In Lateral Mesoderm Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Determination Of Left/right Symmetry Anterior/posterior Pattern Specification Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Nodal Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Hepatocyte Differentiation Cellular Response To Cytokine Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Protein Localization To Nucleus Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Rhythmic Process Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Signaling by NODAL Signaling by Activin Germ layer formation at gastrulation Formation of axial mesoderm	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988) General cognitive ability ( 29844566)	Bell's palsy ( 33602968)
Interacting Genes		68 interacting genes: ACTMAP AOC1 ARID5A ATP23 ATXN1L BATF2 C10orf55 CEACAM6 CFAP68 CREBBP CRX CRYBA1 CYSRT1 DAZAP2 DRAP1 FAM168B FAM83A FOXD2 FOXG1 HDHD3 HEY1 HLX HOXA1 HSF4 KLHL26 KRTAP11-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP7-1 LASP1 MAGED1 MGAT5B MSX2 NKX2-5 NOTO OXER1 PLA2G10 PNMA5 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM46 RBPMS2 RNF144B SERGEF SMAD2 SMAD3 SMAD4 SOX14 SOX4 TEKT5 TFG TLX3 TSC1 UBAP2 UFSP1 ZC3H10 ZIC1 ZNF34 ZNF503	128 interacting genes: AGRN AKAP9 ARHGEF16 ARID5A ARNT2 BAG3 BAG4 BARD1 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CAPN7 CCDC120 CCDC33 CDC23 CERCAM CFAP206 CHERP DAB1 DAZAP2 DDX6 DLX4 DLX5 DMRT2 EIF3J EIF4E2 EP300 ERCC3 FAM83A FOXD2 FOXH1 FOXI1 FXR1 FXR2 GATA5 GLRA1 GLYCTK GPANK1 GPR135 GRAP2 HEMK1 HGS HIVEP1 HNRNPH1 HNRNPLL HOXC9 HSF2BP HUNK KPNA2 KPNA6 KRTAP19-5 KRTAP6-1 KRTAP6-3 LARP4B LENG8 LONRF1 MAPK1IP1L MAPK3 MDFI MEOX2 MGAT5B MKRN3 MPC1 MSX2 NAF1 NGFR NOTCH1 NOTO NPAS4 NUMBL PHF1 PITX1 PJA1 PJA2 PLK1 PNMA5 POM121 PRKAB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMF1 RAMAC RBFOX1 RBFOX2 RBM23 RBPMS RBPMS2 RFX1 RHOXF2 RNF6 RNF8 ROR2 RUSC1 RXFP4 SIM2 SIRT7 SMAP2 SMN1 SMN2 SNRPC SOX10 SOX5 TBX6 TFG TIAL1 TLX3 TRAF4 TRIM28 TSGA10IP TTC23 TTC32 TUBA4A UNC5A VASP VENTX XIAP YTHDF1 ZFYVE26 ZIC1 ZNF488 ZNF688
Entrez ID		8928	9500
HPRD ID		04689	02202
Ensembl ID		ENSG00000160973	ENSG00000179222
Uniprot IDs		O75593	Q9Y5V3
PDB IDs		5XOC 7YZB
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Embryonic Morphogenesis Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Cardiac Conduction System Development DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding SMAD Protein Complex Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Heteromeric SMAD Protein Complex Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Cardiac Septum Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of DNA-templated Transcription Regionalization Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Ventricular Septum Morphogenesis I-SMAD Binding Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Pattern Specification Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Activin Responsive Factor Complex Gastrulation Paraxial Mesoderm Morphogenesis Heart Valve Morphogenesis Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cell Differentiation Embryonic Pattern Specification Cardiac Muscle Tissue Development SMAD Protein Signal Transduction Chromatin Binding Mesoderm Morphogenesis R-SMAD Binding Outflow Tract Septum Morphogenesis Cardiac Epithelial To Mesenchymal Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Gene Expression RNA Polymerase II Transcription Regulator Complex Tube Morphogenesis	Regulation Of RNA Metabolic Process Cytoplasmic Stress Granule Sequence-specific Double-stranded DNA Binding Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression DNA Binding Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process System Development Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleus Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Nucleic Acid Binding Nervous System Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Pattern Specification Process Embryonic Morphogenesis MRNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Identical Protein Binding Negative Regulation Of RNA Metabolic Process Cytoplasmic Ribonucleoprotein Granule Nuclear Androgen Receptor Binding RNA Binding Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Protein Import Into Nucleus Regulation Of Nucleocytoplasmic Transport Viral Penetration Into Host Nucleus Regulation Of RNA Splicing Transcription Regulator Complex
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