RAB11A and MYO5A

Number of citations of the paper that reports this interaction (PubMedID 19009530)
0

Data Source:
HPRD (two hybrid)

		RAB11A	MYO5A
Description		RAB11A, member RAS oncogene family	myosin VA
Image
GO Annotations	Cellular Component	Golgi Membrane Spindle Pole Cytoplasm Endosome Multivesicular Body Golgi Apparatus Trans-Golgi Network Centrosome Centriole Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Trans-Golgi Network Membrane Protein-containing Complex Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynaptic Endosome Postsynaptic Recycling Endosome Glutamatergic Synapse	Ruffle Cytoplasm Lysosome Early Endosome Late Endosome Peroxisome Endoplasmic Reticulum Cytosol Actin Filament Actin Cytoskeleton Membrane Myosin Complex Growth Cone Cytoplasmic Vesicle Vesicle Filopodium Tip Insulin-responsive Compartment Melanosome Neuron Projection Recycling Endosome Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Microtubule Binding Hydrolase Activity Syntaxin Binding Myosin V Binding Dynein Light Intermediate Chain Binding	Microfilament Motor Activity Nucleotide Binding RNA Binding Cytoskeletal Motor Activity Actin Binding Catalytic Activity Protein Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity Small GTPase Binding Actin Filament Binding
	Biological Process	Mitotic Cytokinesis Exocytosis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Mitotic Metaphase Chromosome Alignment Positive Regulation Of Epithelial Cell Migration Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Regulation Of Cytokinesis Protein Localization To Cell Surface Multivesicular Body Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Vesicle-mediated Transport To The Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Synaptic Vesicle Endosomal Processing Amyloid-beta Clearance By Transcytosis Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Exosomal Secretion Regulation Of Endocytic Recycling	Post-Golgi Vesicle-mediated Transport Endocytosis Actin Filament Organization Protein Transport Vesicle-mediated Transport Actin Filament-based Movement Vesicle Transport Along Actin Filament Melanosome Transport Cellular Response To Insulin Stimulus Protein Localization To Plasma Membrane Regulation Of Golgi Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Vasopressin regulates renal water homeostasis via Aquaporins Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation Insulin processing FCGR3A-mediated phagocytosis Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate
Diseases			Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean corpuscular hemoglobin ( 27863252 29403010 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 27863252 29403010 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Mean platelet volume ( 32888494) Metabolite levels (Pyroglutamine) ( 23934736)
Interacting Genes		32 interacting genes: ARF6 CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB13 RAB3IL1 RAB3IP RAB8A RABGGTB RCHY1 SEC13 SNCA STX4 TBXA2R TDP2 WDR44	20 interacting genes: AKAP9 BMF CALM1 DLGAP1 DYNLL1 DYNLL2 ERG KIF5B MLPH NDEL1 NEFL PDE4B PRPH RAB11A RAB27A RAB3A RPH3A TRIM2 TRIM3 USP7
Entrez ID		8766	4644
HPRD ID		05715	01179
Ensembl ID		ENSG00000103769	ENSG00000197535
Uniprot IDs		P62491	A0A8I5KTF1 A0A8J8YWI7 A8CDT9 Q9UES4 Q9Y4I1
PDB IDs		1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ 6DJL 6IXV 8VOF	4D07 4J5L 4LLI 4LX1 4LX2 5JCY 5JCZ
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Protein Localization Recycling Endosome Endosome Small GTPase Binding Recycling Endosome Membrane Organelle Localization Establishment Of Localization In Cell Vesicle-mediated Transport To The Plasma Membrane Cellular Localization Organelle Localization By Membrane Tethering Membrane Docking Intracellular Transport Negative Regulation Of Adiponectin Secretion Endosomal Transport Post-Golgi Vesicle-mediated Transport Midbody Protein Localization To Plasma Membrane Cytosol Exocytosis Golgi To Plasma Membrane Transport Protein Localization To Cell Periphery Endocytic Recycling Cytoplasmic Vesicle Localization Within Membrane Kinetochore Golgi Vesicle Transport Cytoplasmic Vesicle Membrane Negative Regulation Of Cell Projection Organization Protein Localization To Membrane Neuron Projection Establishment Of Protein Localization To Plasma Membrane Golgi Apparatus Cytoplasm Vesicle Docking Synaptic Vesicle Regulation Of Protein Localization Organelle Assembly Organelle Organization Regulation Of Vesicle-mediated Transport Regulation Of Organelle Assembly Secretion By Cell Protein Localization To Cleavage Furrow Endocytic Vesicle Regulation Of Secretion By Cell Regulation Of Receptor Recycling Positive Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Cell Communication	Establishment Of Vesicle Localization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Myosin V Binding Establishment Of Localization In Cell Retrograde Axonal Transport Protein-containing Complex Binding Establishment Of Melanosome Localization Melanosome Localization Melanosome Transport Pigment Granule Transport Pigment Granule Localization Regulation Of Transport Centrosome Centrosome Localization Exosomal Secretion Synaptic Vesicle Transport Microtubule Associated Complex Synaptic Vesicle Membrane Modulation Of Chemical Synaptic Transmission Synaptic Vesicle Microtubule-based Process Positive Regulation Of Regulated Secretory Pathway Lysosome Localization Transport Along Microtubule Vesicle Axonal Transport Neurofilament Cytoskeleton Organization Microtubule-based Movement Cytoskeleton-dependent Intracellular Transport Cytosol Microtubule-based Transport Axo-dendritic Transport Positive Regulation Of Exocytosis Cytoskeleton Organelle Transport Along Microtubule Protein Transport Vesicle-mediated Transport In Synapse Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Organization Organelle Organization Secretory Granule Regulation Of Intracellular Transport Intracellular Transport Regulation Of Cellular Localization Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?