MYO5A and PRPH

Number of citations of the paper that reports this interaction (PMID 12403814)
20

Data Source:
HPRD (in vitro, in vivo)

		MYO5A	PRPH
Gene Name		myosin VA (heavy chain 12, myoxin)	peripherin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Photoreceptor Outer Segment Cytoplasm Lysosome Early Endosome Late Endosome Peroxisome Endoplasmic Reticulum Golgi Apparatus Cytosol Intermediate Filament Actin Filament Membrane Myosin Complex Growth Cone Vesicle Filopodium Tip Insulin-responsive Compartment Microtubule Plus-end Melanosome Actomyosin Neuron Projection Neuronal Cell Body Recycling Endosome Extracellular Vesicular Exosome	Intermediate Filament Neurofilament Membrane Photoreceptor Outer Segment Membrane C-fiber Type III Intermediate Filament Extracellular Vesicular Exosome
	Molecular Function	Microfilament Motor Activity Actin Binding Calcium Ion Binding Calmodulin Binding ATP Binding Rab GTPase Binding Poly(A) RNA Binding	Structural Molecule Activity
	Biological Process	Transport Exocytosis Post-Golgi Vesicle-mediated Transport Synaptic Transmission Visual Perception Protein Transport Vesicle-mediated Transport Actin Filament-based Movement Vesicle Transport Along Actin Filament Insulin Secretion Melanocyte Differentiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Locomotion Involved In Locomotory Behavior Secretory Granule Localization Melanosome Transport Cellular Response To Insulin Stimulus Melanin Biosynthetic Process Odontogenesis Myelination Long-chain Fatty Acid Biosynthetic Process Cellular Protein Metabolic Process Synapse Organization Endoplasmic Reticulum Localization Membrane Organization Protein Localization To Plasma Membrane Regulation Of Golgi Organization	Intermediate Filament Cytoskeleton Organization
Pathways		Peptide hormone metabolism Translocation of GLUT4 to the plasma membrane Insulin processing Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Prostate cancer ( 21743467)
Protein-Protein Interactions		11 interactors: BMF DLGAP1 DYNLL1 DYNLL2 MLPH NEFL PRPH RAB11A RAB27A TRIM2 TRIM3	5 interactors: KRT15 LMNB1 MYO5A PRPH2 VIM
Entrez ID		4644	5630
HPRD ID		01179	01365
Ensembl ID		ENSG00000197535
Uniprot IDs		A8CDT9 F8WE88 G3V394 Q9UES4 Q9Y4I1	B3KWQ6 P41219
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Multivesicular Body Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Melanosome Localization Exosomal Secretion Cellular Pigmentation Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Pigmentation Intrinsic Apoptotic Signaling Pathway Melanosome Transport Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Endosome Organization Pigment Granule Transport Vesicle Localization Establishment Of Melanosome Localization Melanocyte Differentiation Positive Regulation Of Intracellular Transport Intermediate Filament Cytoskeleton Organization Neuroepithelial Cell Differentiation Intermediate Filament-based Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Antigen Processing And Presentation Regulation Of Apoptotic Process Anatomical Structure Development Microtubule-based Process Regulation Of Protein Localization Rab Protein Signal Transduction Developmental Pigmentation Regulation Of Cell Death Apoptotic Signaling Pathway Positive Regulation Of Constitutive Secretory Pathway Multivesicular Body Assembly Regulation Of Multivesicular Body Size Complement-dependent Cytotoxicity Synaptic Target Recognition Positive Regulation Of Axonogenesis Developmental Process Positive Regulation Of Organelle Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Organelle Localization Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Intracellular Transport Cytotoxic T Cell Degranulation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II	Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament-based Movement Execution Phase Of Apoptosis Tissue Development Visual Perception Sensory Perception Of Light Stimulus Endoplasmic Reticulum Localization Vesicle Transport Along Actin Filament Response To Low Light Intensity Stimulus Epithelium Development Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Locomotion Involved In Locomotory Behavior Bergmann Glial Cell Differentiation Secretory Granule Localization Camera-type Eye Development Response To Light Intensity Eye Development Long-chain Fatty Acid Biosynthetic Process Melanin Biosynthetic Process Melanin Metabolic Process Intermediate Filament Organization Lens Fiber Cell Development Secondary Metabolite Biosynthetic Process Astrocyte Development Epithelial Cell Differentiation Sensory Organ Development Muscle Filament Sliding Actin-myosin Filament Sliding Actin Filament-based Process Melanosome Transport Lens Fiber Cell Differentiation Pigment Granule Transport Anatomical Structure Development Establishment Of Melanosome Localization Melanocyte Differentiation Intermediate Filament Cytoskeleton Organization Melanosome Localization Insulin Secretion Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Neuroepithelial Cell Differentiation Sensory Perception Developmental Process SMAD Protein Signal Transduction Pigment Biosynthetic Process Cellular Pigmentation Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	accumulated albeit autoantibodies autoreactive b c57bl dynamics epitope follicular frequencies genesis heterogeneous infiltrating insulitis invaded islet islets isotype likewise octameric peripherin peritoneum prediabetic preferentially proliferates spleen subsets switched unfolded
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	accumulated albeit autoantibodies autoreactive b c57bl dynamics epitope follicular frequencies genesis heterogeneous infiltrating insulitis invaded islet islets isotype likewise octameric peripherin peritoneum prediabetic preferentially proliferates spleen subsets switched unfolded
Tagcloud (Intersection) ?