RAB11A and SEC13

Number of citations of the paper that reports this interaction (PMID 10747849)
4

Data Source:
BioGRID (two hybrid)

		RAB11A	SEC13
Gene Name		RAB11A, member RAS oncogene family	SEC13 homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Mitochondrion Multivesicular Body Trans-Golgi Network Kinetochore Microtubule Cytosol Plasma Membrane Transport Vesicle Axon Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome	Golgi Membrane Kinetochore Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Nuclear Pore Outer Ring Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Syntaxin Binding Myosin V Binding	Protein Binding
	Biological Process	Cytokinesis Renal Water Homeostasis Water Transport Intracellular Protein Transport Exocytosis Organelle Organization Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Transmembrane Transport Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Exosomal Secretion	Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating MRNA Transport Membrane Organization
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Vasopressin regulates renal water homeostasis via Aquaporins Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Aquaporin-mediated transport Anchoring of the basal body to the plasma membrane	Mitotic Prometaphase Diseases of glycosylation Separation of Sister Chromatids Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Mitotic Anaphase Antigen Presentation: Folding, assembly and peptide loading of class I MHC M Phase Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Cell Cycle, Mitotic Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Resolution of Sister Chromatid Cohesion Defective ALG12 causes ALG12-CDG (CDG-1g) Mitotic Metaphase and Anaphase Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB3IL1 RABGGTB RCHY1 SEC13 STX4 TBXA2R TDP2 WDR44 YWHAG	8 interactors: CLDN12 EGFR NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44
Entrez ID		8766	6396
HPRD ID		05715	02538
Ensembl ID		ENSG00000103769	ENSG00000157020
Uniprot IDs		P62491	A8MWR8 B4DXJ1 P55735
PDB IDs		1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P	3BG0 3BG1
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization Establishment Of Localization In Cell Cellular Localization Organelle Localization Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Vesicle Localization Vesicle Localization Transport Exocytosis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Membrane Organization Intracellular Transport Regulation Of Signaling Golgi Vesicle Transport Cell Death Death Insulin Secretion Secretion By Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Synaptic Transmission Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulated Secretory Pathway Regulation Of Synaptic Plasticity Regulation Of Body Fluid Levels Amyloid Precursor Protein Catabolic Process Cell-cell Signaling Peptide Hormone Secretion Secretion Peptide Secretion Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway Signaling Apoptotic Process Cell Cycle Cell Communication Negative Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Cycle Process Negative Regulation Of Kinase Activity Hormone Secretion Regulation Of Protein Kinase Activity Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process	Membrane Organization COPII Vesicle Coating COPII-coated Vesicle Budding Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Cytoplasmic Transport Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Cellular Component Assembly Protein Localization Establishment Of Organelle Localization Protein Complex Assembly Organelle Localization Cellular Localization Endomembrane System Organization Membrane Budding Alkanesulfonate Metabolic Process Regulation Of Multivesicular Body Size Multivesicular Body Assembly Cellular Protein Localization Protein Localization To Organelle ER To Golgi Vesicle-mediated Transport Protein Transport Response To Calcium Ion Intracellular Transport Protein Import Into Nucleus, Docking Multivesicular Body Organization Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Endosome Size Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Activation Of Phospholipase A2 Activity Exosomal Secretion Regulation Of Protein Localization Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Exit From Endoplasmic Reticulum Establishment Of Localization In Cell Vesicle Organization Response To Cobalamin Response To UV-A Regulation Of Protein Exit From Endoplasmic Reticulum Response To Hydroxyisoflavone Nuclear Pore Complex Assembly Establishment Of Protein Localization To Membrane
Tagcloud ?		c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular	antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Difference) ?		c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular	antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Intersection) ?