RAB11A and RAB11FIP2

Number of citations of the paper that reports this interaction (PubMedID 11495908)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		RAB11A	RAB11FIP2
Description		RAB11A, member RAS oncogene family	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Golgi Membrane Spindle Pole Cytoplasm Endosome Multivesicular Body Golgi Apparatus Trans-Golgi Network Centrosome Centriole Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Trans-Golgi Network Membrane Protein-containing Complex Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynaptic Endosome Postsynaptic Recycling Endosome Glutamatergic Synapse	Phagocytic Cup Nucleoplasm Endosome Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cell Projection Recycling Endosome Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Microtubule Binding Hydrolase Activity Syntaxin Binding Myosin V Binding Dynein Light Intermediate Chain Binding	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Mitotic Cytokinesis Exocytosis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Mitotic Metaphase Chromosome Alignment Positive Regulation Of Epithelial Cell Migration Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Regulation Of Cytokinesis Protein Localization To Cell Surface Multivesicular Body Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Vesicle-mediated Transport To The Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Synaptic Vesicle Endosomal Processing Amyloid-beta Clearance By Transcytosis Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Exosomal Secretion Regulation Of Endocytic Recycling	Phagocytosis Cell Communication Protein Transport Vesicle-mediated Transport Signaling Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Vasopressin regulates renal water homeostasis via Aquaporins Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean corpuscular hemoglobin ( 27863252 29403010 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 27863252 29403010 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)
Interacting Genes		32 interacting genes: ARF6 CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB13 RAB3IL1 RAB3IP RAB8A RABGGTB RCHY1 SEC13 SNCA STX4 TBXA2R TDP2 WDR44	22 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 SNCA YWHAE YWHAG
Entrez ID		8766	22841
HPRD ID		05715	10548
Ensembl ID		ENSG00000103769	ENSG00000107560
Uniprot IDs		P62491	Q7L804
PDB IDs		1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ 6DJL 6IXV 8VOF	2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Protein Localization Recycling Endosome Endosome Small GTPase Binding Recycling Endosome Membrane Organelle Localization Establishment Of Localization In Cell Vesicle-mediated Transport To The Plasma Membrane Cellular Localization Organelle Localization By Membrane Tethering Membrane Docking Intracellular Transport Negative Regulation Of Adiponectin Secretion Endosomal Transport Post-Golgi Vesicle-mediated Transport Midbody Protein Localization To Plasma Membrane Cytosol Exocytosis Golgi To Plasma Membrane Transport Protein Localization To Cell Periphery Endocytic Recycling Cytoplasmic Vesicle Localization Within Membrane Kinetochore Golgi Vesicle Transport Cytoplasmic Vesicle Membrane Negative Regulation Of Cell Projection Organization Protein Localization To Membrane Neuron Projection Establishment Of Protein Localization To Plasma Membrane Golgi Apparatus Cytoplasm Vesicle Docking Synaptic Vesicle Regulation Of Protein Localization Organelle Assembly Organelle Organization Regulation Of Vesicle-mediated Transport Regulation Of Organelle Assembly Secretion By Cell Protein Localization To Cleavage Furrow Endocytic Vesicle Regulation Of Secretion By Cell Regulation Of Receptor Recycling Positive Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Cell Communication	Vesicle-mediated Transport Endosomal Transport Endocytosis Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Import Into Cell Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Intracellular Transport Myosin V Binding Organelle Localization Establishment Of Protein Localization Regulation Of Endocytic Recycling Endocytic Recycling Regulation Of Biological Quality Vesicle-mediated Transport In Synapse Exocytosis Recycling Endosome Membrane Cellular Localization Secretion By Cell Establishment Of Vesicle Localization Protein Localization To Organelle Synaptic Vesicle Endocytosis Vesicle Localization Protein Sequestering Activity Regulation Of Intracellular Transport Presynaptic Endocytosis Synaptic Vesicle Membrane Synaptic Vesicle Amyloid-beta Clearance By Transcytosis Regulation Of Synapse Organization Secretion Protein Transport Cytoplasm Regulation Of Cellular Localization Positive Regulation Of Endocytosis Postsynaptic Endocytic Zone Glutamatergic Synapse Receptor-mediated Endocytosis GTP Binding Receptor Internalization Regulation Of Transport Clathrin-coated Pit G Protein Activity Regulation Of Protein Localization Protein-macromolecule Adaptor Activity Regulation Of SNARE Complex Assembly Phagocytic Vesicle Protein Localization To Endoplasmic Reticulum
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