RAB11A and RAB11FIP4

Number of citations of the paper that reports this interaction (PubMedID 12470645)
0

Data Source:
HPRD (two hybrid, in vitro)

		RAB11A	RAB11FIP4
Description		RAB11A, member RAS oncogene family	RAB11 family interacting protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Spindle Pole Cytoplasm Endosome Multivesicular Body Golgi Apparatus Trans-Golgi Network Centrosome Centriole Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Trans-Golgi Network Membrane Protein-containing Complex Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynaptic Endosome Postsynaptic Recycling Endosome Glutamatergic Synapse	Extracellular Space Cytoplasm Endosome Golgi Apparatus Centrosome Spindle Cytoskeleton Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Cleavage Furrow Perinuclear Region Of Cytoplasm Recycling Endosome Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Microtubule Binding Hydrolase Activity Syntaxin Binding Myosin V Binding Dynein Light Intermediate Chain Binding	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Mitotic Cytokinesis Exocytosis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Mitotic Metaphase Chromosome Alignment Positive Regulation Of Epithelial Cell Migration Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Regulation Of Cytokinesis Protein Localization To Cell Surface Multivesicular Body Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Vesicle-mediated Transport To The Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Synaptic Vesicle Endosomal Processing Amyloid-beta Clearance By Transcytosis Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Exosomal Secretion Regulation Of Endocytic Recycling	Neural Retina Development Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of G1 To G0 Transition
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Vasopressin regulates renal water homeostasis via Aquaporins Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean corpuscular hemoglobin ( 27863252 29403010 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 27863252 29403010 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Adventurousness ( 30643258) Apolipoprotein A1 levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Facial attractiveness (male raters) ( 30946739) Heel bone mineral density ( 28869591 30598549) Hip circumference adjusted for BMI ( 34021172) Keratoconus ( 33649486) Myocardial infarction ( 33532862)
Interacting Genes		32 interacting genes: ARF6 CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB13 RAB3IL1 RAB3IP RAB8A RABGGTB RCHY1 SEC13 SNCA STX4 TBXA2R TDP2 WDR44	9 interacting genes: ARF6 ECPAS GFI1B MAD2L2 PKNOX1 RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5
Entrez ID		8766	84440
HPRD ID		05715	11466
Ensembl ID		ENSG00000103769	ENSG00000131242
Uniprot IDs		P62491	Q86YS3
PDB IDs		1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ 6DJL 6IXV 8VOF
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Protein Localization Recycling Endosome Endosome Small GTPase Binding Recycling Endosome Membrane Organelle Localization Establishment Of Localization In Cell Vesicle-mediated Transport To The Plasma Membrane Cellular Localization Organelle Localization By Membrane Tethering Membrane Docking Intracellular Transport Negative Regulation Of Adiponectin Secretion Endosomal Transport Post-Golgi Vesicle-mediated Transport Midbody Protein Localization To Plasma Membrane Cytosol Exocytosis Golgi To Plasma Membrane Transport Protein Localization To Cell Periphery Endocytic Recycling Cytoplasmic Vesicle Localization Within Membrane Kinetochore Golgi Vesicle Transport Cytoplasmic Vesicle Membrane Negative Regulation Of Cell Projection Organization Protein Localization To Membrane Neuron Projection Establishment Of Protein Localization To Plasma Membrane Golgi Apparatus Cytoplasm Vesicle Docking Synaptic Vesicle Regulation Of Protein Localization Organelle Assembly Organelle Organization Regulation Of Vesicle-mediated Transport Regulation Of Organelle Assembly Secretion By Cell Protein Localization To Cleavage Furrow Endocytic Vesicle Regulation Of Secretion By Cell Regulation Of Receptor Recycling Positive Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Cell Communication	Protein Localization To Cleavage Furrow Recycling Endosome Membrane Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Recycling Endosome Positive Regulation Of Cilium Assembly Endosome Vesicle Docking Involved In Exocytosis Positive Regulation Of Cytokinesis Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Adiponectin Secretion Protein Localization To Plasma Membrane Early Endosome To Recycling Endosome Transport Cleavage Furrow Vesicle Docking Protein Localization To Cilium Regulation Of Cell Projection Assembly Mitotic Cytokinesis Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Plasma Membrane Endocytic Vesicle Positive Regulation Of Protein Localization To Cell Periphery Protein Transport Endocytic Recycling Organelle Localization By Membrane Tethering Regulation Of Cytokinesis Small GTPase Binding Positive Regulation Of Protein Localization To Membrane Membrane Docking Positive Regulation Of Cell Division Cytoskeleton-dependent Cytokinesis Establishment Of Cell Polarity Protein Localization To Membrane Regulation Of Protein Localization To Centrosome Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Organelle Assembly Regulation Of Cilium Assembly Establishment Of Protein Localization Regulation Of Cell Cycle Process Positive Regulation Of Cell Projection Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Protein Localization To Plasma Membrane Vesicle-mediated Transport To The Plasma Membrane Regulation Of Endocytic Recycling Regulation Of Protein Transport Establishment Of Localization In Cell Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization Establishment Or Maintenance Of Cell Polarity
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