MYO5A and DLGAP1

Number of citations of the paper that reports this interaction (PMID 10844022)
49

Data Source:
BioGRID (pull down)

		MYO5A	DLGAP1
Gene Name		myosin VA (heavy chain 12, myoxin)	discs, large (Drosophila) homolog-associated protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Photoreceptor Outer Segment Cytoplasm Lysosome Early Endosome Late Endosome Peroxisome Endoplasmic Reticulum Golgi Apparatus Cytosol Intermediate Filament Actin Filament Membrane Myosin Complex Growth Cone Vesicle Filopodium Tip Insulin-responsive Compartment Microtubule Plus-end Melanosome Actomyosin Neuron Projection Neuronal Cell Body Recycling Endosome Extracellular Vesicular Exosome	Cellular_component Cell Junction Postsynaptic Membrane Neuronal Postsynaptic Density
	Molecular Function	Microfilament Motor Activity Actin Binding Calcium Ion Binding Calmodulin Binding ATP Binding Rab GTPase Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Transport Exocytosis Post-Golgi Vesicle-mediated Transport Synaptic Transmission Visual Perception Protein Transport Vesicle-mediated Transport Actin Filament-based Movement Vesicle Transport Along Actin Filament Insulin Secretion Melanocyte Differentiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Locomotion Involved In Locomotory Behavior Secretory Granule Localization Melanosome Transport Cellular Response To Insulin Stimulus Melanin Biosynthetic Process Odontogenesis Myelination Long-chain Fatty Acid Biosynthetic Process Cellular Protein Metabolic Process Synapse Organization Endoplasmic Reticulum Localization Membrane Organization Protein Localization To Plasma Membrane Regulation Of Golgi Organization	Synaptic Transmission
Pathways		Peptide hormone metabolism Translocation of GLUT4 to the plasma membrane Insulin processing Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Cardiac Troponin-T levels ( 23247143) Eating disorders ( 22911880) Economic and political preferences (time) ( 22566634) Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: BMF DLGAP1 DYNLL1 DYNLL2 MLPH NEFL PRPH RAB11A RAB27A TRIM2 TRIM3	21 interactors: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1
Entrez ID		4644	9229
HPRD ID		01179	09260
Ensembl ID		ENSG00000197535	ENSG00000170579
Uniprot IDs		A8CDT9 F8WE88 G3V394 Q9UES4 Q9Y4I1	A8MXQ8 B7Z2J5 O14490
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Multivesicular Body Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Melanosome Localization Exosomal Secretion Cellular Pigmentation Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Pigmentation Intrinsic Apoptotic Signaling Pathway Melanosome Transport Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Endosome Organization Pigment Granule Transport Vesicle Localization Establishment Of Melanosome Localization Melanocyte Differentiation Positive Regulation Of Intracellular Transport Intermediate Filament Cytoskeleton Organization Neuroepithelial Cell Differentiation Intermediate Filament-based Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Antigen Processing And Presentation Regulation Of Apoptotic Process Anatomical Structure Development Microtubule-based Process Regulation Of Protein Localization Rab Protein Signal Transduction Developmental Pigmentation Regulation Of Cell Death Apoptotic Signaling Pathway Positive Regulation Of Constitutive Secretory Pathway Multivesicular Body Assembly Regulation Of Multivesicular Body Size Complement-dependent Cytotoxicity Synaptic Target Recognition Positive Regulation Of Axonogenesis Developmental Process Positive Regulation Of Organelle Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Organelle Localization Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Intracellular Transport Cytotoxic T Cell Degranulation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II	Cell-cell Signaling Synaptic Transmission Protein Localization To Synapse Receptor Localization To Synapse Nervous System Development Vocalization Behavior Receptor Clustering Learning Dendritic Spine Organization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Locomotion Social Behavior Neuron Projection Morphogenesis Membrane Depolarization Neuron Development Signaling Cell Communication Learning Or Memory Cell Morphogenesis Involved In Differentiation Regulation Of Membrane Potential Dendritic Spine Morphogenesis Cognition Nucleotide Phosphorylation Neuron Differentiation Regulation Of Signaling Cell Projection Organization Neuron Projection Development Neurological System Process Cell Projection Morphogenesis Synapse Organization Cell Part Morphogenesis Dendritic Spine Development Neurogenesis Behavior Protein Localization To Membrane Anatomical Structure Development System Development Regulation Of Ion Transmembrane Transport Anatomical Structure Morphogenesis Cell Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Single-organism Behavior Generation Of Neurons Regulation Of Receptor Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential Developmental Process Memory Multicellular Organismal Development
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	18p11 aided blindness cataracts centimorgans chorioretinal clul1 compiled elastin emilin2 interfacer intronic lipin lpin2 microfibril mrcl3 mrlc2 myom1 myomesin myopia myosin myp2 pedigree positional prioritizing segregated tgifbeta underway zfp161
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	18p11 aided blindness cataracts centimorgans chorioretinal clul1 compiled elastin emilin2 interfacer intronic lipin lpin2 microfibril mrcl3 mrlc2 myom1 myomesin myopia myosin myp2 pedigree positional prioritizing segregated tgifbeta underway zfp161
Tagcloud (Intersection) ?