RAB11A and MYO5B

Number of citations of the paper that reports this interaction (PMID 11408590)
102

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB11A	MYO5B
Gene Name		RAB11A, member RAS oncogene family	myosin VB
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Mitochondrion Multivesicular Body Trans-Golgi Network Kinetochore Microtubule Cytosol Plasma Membrane Transport Vesicle Axon Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome	Myosin Complex Cytoplasmic Vesicle Membrane Protein Complex Apical Cortex Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Syntaxin Binding Myosin V Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Rab GTPase Binding
	Biological Process	Cytokinesis Renal Water Homeostasis Water Transport Intracellular Protein Transport Exocytosis Organelle Organization Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Transmembrane Transport Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Exosomal Secretion	Renal Water Homeostasis Water Transport Metabolic Process Protein Transport Vesicle-mediated Transport Endosome Localization Transmembrane Transport
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Vasopressin regulates renal water homeostasis via Aquaporins Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Aquaporin-mediated transport Anchoring of the basal body to the plasma membrane	Vasopressin regulates renal water homeostasis via Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB3IL1 RABGGTB RCHY1 SEC13 STX4 TBXA2R TDP2 WDR44 YWHAG	14 interactors: AMOTL2 BNIP2 COIL CXCR2 KIAA1549 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 RAB8A SMAD3 TCF4 TRIM54
Entrez ID		8766	4645
HPRD ID		05715	07582
Ensembl ID		ENSG00000103769	ENSG00000167306
Uniprot IDs		P62491	Q7Z7A5 Q9H6Y6 Q9ULV0
PDB IDs		1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization Establishment Of Localization In Cell Cellular Localization Organelle Localization Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Vesicle Localization Vesicle Localization Transport Exocytosis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Membrane Organization Intracellular Transport Regulation Of Signaling Golgi Vesicle Transport Cell Death Death Insulin Secretion Secretion By Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Synaptic Transmission Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulated Secretory Pathway Regulation Of Synaptic Plasticity Regulation Of Body Fluid Levels Amyloid Precursor Protein Catabolic Process Cell-cell Signaling Peptide Hormone Secretion Secretion Peptide Secretion Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway Signaling Apoptotic Process Cell Cycle Cell Communication Negative Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Cycle Process Negative Regulation Of Kinase Activity Hormone Secretion Regulation Of Protein Kinase Activity Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process	Rab Protein Signal Transduction Vesicle Localization Exocytosis Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Organelle Localization Insulin Secretion Involved In Cellular Response To Glucose Stimulus Establishment Of Vesicle Localization Secretion By Cell Cellular Pigmentation Ras Protein Signal Transduction Secretion Positive Regulation Of Cell Migration Establishment Of Organelle Localization Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Signaling Pigmentation Regulation Of Protein Localization Regulation Of Vesicle-mediated Transport Cell Communication Protein Transport Protein Secretion Vesicle-mediated Transport Response To Glucose Establishment Of Protein Localization Chemical Homeostasis Intracellular Protein Transport Positive Regulation Of Cell Morphogenesis Involved In Differentiation Response To Stimulus Positive Regulation Of Cell Development Renal Water Homeostasis Response To Carbohydrate Cellular Response To Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Epithelial To Mesenchymal Transition Glucose Homeostasis Signal Transduction Intracellular Signal Transduction Regulation Of Cell Migration DNA-templated Transcription, Initiation Protein Localization Small GTPase Mediated Signal Transduction Regulation Of Protein Transport Regulation Of Cell Motility Insulin Secretion Water Transport
Tagcloud ?		c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular	alleles comprising disequilibrium dyslexia english enrichment explores german germany hereditary language linkage loci minor nedd4l nominal reading relevance replicated rs12606138 rs555879 rs8094327 scerri sets snp snps speaking spelling substantiate
Tagcloud (Difference) ?		c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular	alleles comprising disequilibrium dyslexia english enrichment explores german germany hereditary language linkage loci minor nedd4l nominal reading relevance replicated rs12606138 rs555879 rs8094327 scerri sets snp snps speaking spelling substantiate
Tagcloud (Intersection) ?