GRM5 and RGS12

  • Number of citations: 0 (PubMedID 9651375)
  • Data Source: HPRD (in vitro)

GRM5

RGS12

Name glutamate metabotropic receptor 5 regulator of G protein signaling 12
Structure PDB 3LMK PDB 2EBZ
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs None
GWAS
  • Attention deficit hyperactivity disorder ( 22012869 )
  • Blond vs. brown/black hair color ( 30531825 )
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444 )
  • Depression ( 33859377 )
  • Fish- and plant-related diet ( 32066663 )
  • General factor of neuroticism ( 30867560 )
  • Hair color ( 30664655 )
  • Hypertension ( 31879980 )
  • Neurociticism ( 29500382 )
  • Nonsyndromic cleft lip ( 31609978 )
  • Oily fish consumption ( 32066663 )
  • Pork consumption ( 32066663 )
  • Retinal detachment ( 31816047 )
  • Retinal detachment or retinal break ( 31816047 )
  • Rheumatoid arthritis (ACPA-negative) ( 24532677 )
  • Skin pigmentation ( 30664655 31315583 )
  • Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583 )
  • Skin, hair and eye pigmentation (multivariate analysis) ( 30664655 )
  • Tanning ( 19340012 )
  • Adult body size ( 32376654 )
  • Coronary artery disease ( 29212778 )
  • Creatinine levels ( 29403010 )
  • Estimated glomerular filtration rate ( 30604766 31015462 )
  • Glomerular filtration rate ( 29403010 )
  • Hepatocyte growth factor levels ( 25998175 )
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695 )
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401 )
  • Medication use (HMG CoA reductase inhibitors) ( 31015401 )
  • Platelet count ( 29403010 )
  • Serum albumin levels ( 29403010 )
  • Total cholesterol levels ( 29403010 33339817 )
  • Tuberculosis ( 29036319 )
  • Worry too long after an embarrassing experience ( 29500382 )
Interacting Genes 20 interacting genes: ACTN1 CALM1 CALM2 CALM3 CAMK2A EFNB2 FLNA GPRASP1 HOMER1 HOMER3 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCQ PRKCZ RGS12 SIAH1 TAMALIN 17 interacting genes: ARAF CACNA1B CXCR2 EEF1A1 GNAI1 GNAI2 GNAI3 GRM2 GRM5 HRAS MAP2K2 MTNR1A NPY2R PLCB1 PLCB3 PM20D2 YWHAG
Entrez ID 2915 6002
HPRD ID 04980 03943
Ensembl ID ENSG00000168959 ENSG00000159788
Uniprot IDs A8K5P7 P41594 O14924
PDB IDs 3LMK 4OO9 5CGC 5CGD 6N4X 6N4Y 6N50 6N51 6N52 7FD8 7FD9 8T6J 8T7H 8T8M 8TAO 8X0B 8X0C 8X0D 8X0E 8X0F 8X0G 8X0H 2EBZ 2KV8
GO Terms Enriched among Interactors