BCL2L1 and BCL2L11

  • Number of citations of the paper that reports this interaction (PMID 16697956)
  • 236
  • Data Source:
  • HPRD (in vivo, in vitro)

BCL2L1

BCL2L11

Gene Name BCL2-like 1 BCL2-like 11 (apoptosis facilitator)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic lymphocytic leukemia ( 18758461)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Primary sclerosing cholangitis ( 21151127)
Protein-Protein Interactions 79 interactors: ACTB AKT1 ANTXR1 APAF1 AVEN BAD BAG1 BAK1 BAX BBC3 BCAP31 BCL2 BCL2L10 BCL2L11 BCL2L12 BCL2L14 BCLAF1 BECN1 BID BIK BLK BMF BNIP1 BNIP3 BNIP3L BNIPL CAPN1 CASP1 CASP8 CASP9 CDKN2A CFLAR CRYAA CRYAB CYCS DOCK7 EDRF1 FBP1 FKBP8 GLOD4 HRK IKZF3 IRS1 IRS2 LARP1 MAPK8 MCL1 METTL23 MOAP1 MTOR NLRP1 PARK7 PDIA4 PLD3 PMAIP1 PPHLN1 PPP1CA PSEN1 PSEN2 PTN RAD9A RAF1 RBM5 RTN1 RTN4 SIVA1 SNCA SPNS1 TLE1 TMBIM6 TP53 TP53BP2 TPT1 UBR1 UHRF2 VDAC1 ZFYVE1 ZHX1 ZNF219 26 interactors: AKT1 APP ATP6V1G1 AURKB BCL2 BCL2A1 BCL2L1 BCL2L2 BTK DYNLL1 DYNLL2 FEM1C FGL1 GNB2L1 GTF2I MAGEA11 MAPK10 MAPK8 MAPK9 MCL1 MEX3D RIOK3 SMARCB1 TRIM2 VDAC1 YWHAB
Entrez ID 598 10018
HPRD ID 02497 04828
Ensembl ID ENSG00000171552 ENSG00000153094
Uniprot IDs Q07817 Q5TE63 O43521
PDB IDs 1BXL 1G5J 1LXL 1MAZ 1R2D 1R2E 1R2G 1R2H 1R2I 1YSG 1YSI 1YSN 2B48 2LP8 2LPC 2M03 2M04 2O1Y 2O2M 2O2N 2P1L 2PON 2YJ1 2YQ6 2YQ7 2YXJ 3CVA 3FDL 3FDM 3INQ 3IO8 3PL7 3QKD 3R85 3SP7 3SPF 3ZK6 3ZLN 3ZLO 3ZLR 4A1U 4A1W 4AQ3 4EHR 4HNJ 4IEH 1F95 2K7W 2NL9 2V6Q 2VM6 2WH6 2YQ6 3D7V 3FDL 3IO8 3IO9 3KJ0 3KJ1 3KJ2 4B4S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aacr  antiapoptotic  antiestrogens  aromatase  competitive  deprivation  drives  escaped  estrogen  eventually  fulvestrant  hcc1428  junb  kinome  letrozole  lted  mcf7  ovariectomized  parental  pharmacologic  plk1  polo  potently  recur  res  rnai  top  volasertib  xl 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Difference) ?
aacr  antiapoptotic  antiestrogens  aromatase  competitive  deprivation  drives  escaped  estrogen  eventually  fulvestrant  hcc1428  junb  kinome  letrozole  lted  mcf7  ovariectomized  parental  pharmacologic  plk1  polo  potently  recur  res  rnai  top  volasertib  xl 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Intersection) ?