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PPAP2B and BCAR1
Number of citations of the paper that reports this interaction (PMID
16099422
)
9
Data Source:
HPRD
(in vitro)
PPAP2B
BCAR1
Gene Name
phosphatidic acid phosphatase type 2B
breast cancer anti-estrogen resistance 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Apparatus
Plasma Membrane
Adherens Junction
Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Ruffle
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Lamellipodium
Molecular Function
Phosphoprotein Phosphatase Activity
Integrin Binding
Protein Binding
Phosphatidate Phosphatase Activity
Sphingosine-1-phosphate Phosphatase Activity
Lipid Phosphatase Activity
Signal Transducer Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Biological Process
Blood Vessel Development
Gastrulation With Mouth Forming Second
Negative Regulation Of Protein Phosphorylation
Lipid Metabolic Process
Phospholipid Metabolic Process
Sphingolipid Metabolic Process
Germ Cell Migration
Dephosphorylation
Regulation Of Wnt Signaling Pathway
Sphingolipid Biosynthetic Process
Homotypic Cell-cell Adhesion
Small Molecule Metabolic Process
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Endothelial Cell Migration
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cell-cell Adhesion
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Wound Healing
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Protein Stabilization
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Bergmann Glial Cell Differentiation
Regulation Of Sphingolipid Mediated Signaling Pathway
Regulation Of Cell Growth
Actin Filament Organization
Cell Adhesion
Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Blood Coagulation
Cell Proliferation
Insulin Receptor Signaling Pathway
Positive Regulation Of Endothelial Cell Migration
Cell Migration
Platelet Activation
Positive Regulation Of Cell Migration
Cellular Response To Hepatocyte Growth Factor Stimulus
Regulation Of Apoptotic Process
Platelet-derived Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Hepatocyte Growth Factor Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Cell Division
Cell Chemotaxis
Pathways
Sphingolipid metabolism
Metabolism of lipids and lipoproteins
Sphingolipid de novo biosynthesis
Signaling by PDGF
Signaling by VEGF
Downstream signal transduction
p130Cas linkage to MAPK signaling for integrins
Integrin alphaIIb beta3 signaling
Platelet activation, signaling and aggregation
Platelet Aggregation (Plug Formation)
VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS
Airflow obstruction (
22837378
)
Coronary heart disease (
21846871
21378988
21378990
)
Crohn's disease (time to surgery) (
23665963
)
Protein-Protein Interactions
3 interactors:
APP
BCAR1
SHC1
52 interactors:
ABL1
AJUBA
ARHGAP32
BMX
CASP3
CD2AP
CRK
CRKL
CSPG4
DOCK1
E2F2
EFS
ESR1
FES
FXYD6
FYB
FYN
GRB2
GSN
HCK
HSPA5
INPPL1
LCK
LYN
MMP14
NCK1
NEDD9
NPHP1
PIK3R1
PKD1
PPAP2B
PPP1R15A
PTK2
PTK2B
PTPN1
PTPN12
PTPRA
PTPRF
PTPRH
PXN
RAN
RAPGEF1
SH2D3A
SH2D3C
SH3KBP1
SRC
SRCIN1
TRIP6
TUBA4A
UHRF2
VPS11
YWHAZ
Entrez ID
8613
9564
HPRD ID
06179
04248
Ensembl ID
ENSG00000162407
ENSG00000050820
Uniprot IDs
O14495
B2RBL9
B3KWE2
F5H855
P56945
PDB IDs
1WYX
3T6G
Enriched GO Terms of Interacting Partners
?
Platelet Activation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Regulation Of Growth
Regulation Of Protein Tyrosine Kinase Activity
Cell Activation
Response To Wounding
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Regulation Of Receptor Activity
Insulin Receptor Signaling Pathway
Cell Adhesion
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Locomotion
Regulation Of Peptidyl-tyrosine Phosphorylation
Synaptic Growth At Neuromuscular Junction
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Movement Of Cell Or Subcellular Component
Neurotrophin Signaling Pathway
Collateral Sprouting In Absence Of Injury
Response To Insulin
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune System Process
Axon Choice Point Recognition
Regulation Of Cellular Amino Acid Metabolic Process
Hepatocyte Growth Factor Receptor Signaling Pathway
Cellular Response To Hepatocyte Growth Factor Stimulus
Response To Peptide Hormone
Neuron Remodeling
Immune Response-regulating Signaling Pathway
Cellular Response To Organonitrogen Compound
Response To Peptide
Regulation Of Cellular Ketone Metabolic Process
Cellular Response To Growth Factor Stimulus
Cellular Response To Hormone Stimulus
Chemotaxis
Response To Growth Factor
Actin Cytoskeleton Organization
Actin Filament-based Process
Cellular Copper Ion Homeostasis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Signaling
Cell Communication
Cellular Response To Stimulus
Response To Stimulus
Cell Migration
Cell Motility
Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Platelet Activation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Regulation Of Protein Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Locomotion
Cell Surface Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Response To Wounding
ERBB Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Wound Healing
Regulation Of Protein Kinase Activity
Regulation Of Signal Transduction
Cell Adhesion
Regulation Of Cellular Component Organization
Blood Coagulation
Regulation Of Catalytic Activity
Hemostasis
Protein Autophosphorylation
Positive Regulation Of Protein Metabolic Process
Fc Receptor Signaling Pathway
Innate Immune Response
Response To Organonitrogen Compound
Cellular Response To Organonitrogen Compound
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Cellular Response To Peptide Hormone Stimulus
Signal Complex Assembly
Regulation Of Signaling
Tagcloud
?
aldh1a1
anxa1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Intersection)
?