PPAP2B

Gene Name		phosphatidic acid phosphatase type 2B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Adherens Junction Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Phosphoprotein Phosphatase Activity Integrin Binding Protein Binding Phosphatidate Phosphatase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process	Blood Vessel Development Gastrulation With Mouth Forming Second Negative Regulation Of Protein Phosphorylation Lipid Metabolic Process Phospholipid Metabolic Process Sphingolipid Metabolic Process Germ Cell Migration Dephosphorylation Regulation Of Wnt Signaling Pathway Sphingolipid Biosynthetic Process Homotypic Cell-cell Adhesion Small Molecule Metabolic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Endothelial Cell Migration Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cell-cell Adhesion Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Wound Healing Positive Regulation Of Peptidyl-tyrosine Phosphorylation Protein Stabilization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Bergmann Glial Cell Differentiation Regulation Of Sphingolipid Mediated Signaling Pathway
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Coronary heart disease ( 21846871 21378988 21378990)
Protein-protein Interactions		3 interactors: APP BCAR1 SHC1
Entrez ID		8613
HPRD ID		06179
Ensembl ID		ENSG00000162407
Uniprot IDs		O14495
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Regulation Of Epidermal Growth Factor-activated Receptor Activity Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Regulation Of Growth Regulation Of Protein Tyrosine Kinase Activity Cell Activation Response To Wounding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Receptor Activity Insulin Receptor Signaling Pathway Cell Adhesion Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Locomotion Regulation Of Peptidyl-tyrosine Phosphorylation Synaptic Growth At Neuromuscular Junction Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Movement Of Cell Or Subcellular Component Neurotrophin Signaling Pathway Collateral Sprouting In Absence Of Injury Response To Insulin Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune System Process Axon Choice Point Recognition Regulation Of Cellular Amino Acid Metabolic Process Hepatocyte Growth Factor Receptor Signaling Pathway Cellular Response To Hepatocyte Growth Factor Stimulus Response To Peptide Hormone Neuron Remodeling Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of Cellular Ketone Metabolic Process Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Chemotaxis Response To Growth Factor Actin Cytoskeleton Organization Actin Filament-based Process Cellular Copper Ion Homeostasis
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