RUNX2 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 21402695)
  • 5
  • Data Source:
  • BioGRID (enzymatic study)

RUNX2

SMURF2

Gene Name runt-related transcription factor 2 SMAD specific E3 ubiquitin protein ligase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 36 interactors: ALYREF AR AXIN1 CBFB CCNB1 CDK1 CEBPB DVL2 EP300 ETS1 FHL2 FOS HDAC3 HDAC4 HDAC6 HIF1A HIVEP3 JUN KAT6B LEF1 MAP3K4 MSX2 PRKCD RB1 RBM14 SMAD2 SMAD3 SMAD6 SMURF2 SOX9 STUB1 TAF1A UBTF XRCC5 XRCC6 YAP1 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 860 64750
HPRD ID 02566 06901
Ensembl ID ENSG00000124813
Uniprot IDs F8W8U5 Q13950 Q32MY8 Q96DE7 Q9HAU4
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx3  syndromes  unmethylated 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx3  syndromes  unmethylated 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?