RUNX2 and LEF1

  • Number of citations of the paper that reports this interaction (PMID 12551949)
  • 42
  • Data Source:
  • HPRD (in vivo)

RUNX2

LEF1

Gene Name runt-related transcription factor 2 lymphoid enhancer-binding factor 1
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 36 interactors: ALYREF AR AXIN1 CBFB CCNB1 CDK1 CEBPB DVL2 EP300 ETS1 FHL2 FOS HDAC3 HDAC4 HDAC6 HIF1A HIVEP3 JUN KAT6B LEF1 MAP3K4 MSX2 PRKCD RB1 RBM14 SMAD2 SMAD3 SMAD6 SMURF2 SOX9 STUB1 TAF1A UBTF XRCC5 XRCC6 YAP1 28 interactors: ALX4 ALYREF CDX1 CTNNB1 DPYSL2 EP300 KPNA1 KPNA2 MITF NARF NLK NOTCH1 PIAS4 PITX2 RNF138 RUNX2 SETD8 SMAD1 SMAD2 SMAD3 SMAD4 STAT5A SUMO2 TLE1 TLE2 TRA UBTF ZBTB3
Entrez ID 860 51176
HPRD ID 02566 01075
Ensembl ID ENSG00000124813 ENSG00000138795
Uniprot IDs F8W8U5 Q13950 Q32MY8 Q659G9 Q9UJU2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx3  syndromes  unmethylated 
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
Tagcloud (Difference) ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx3  syndromes  unmethylated 
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
Tagcloud (Intersection) ?