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KHSRP and STK3
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
KHSRP
STK3
Description
KH-type splicing regulatory protein
serine/threonine kinase 3
Image
GO Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Protein-containing Complex
Molecular Function
Nucleic Acid Binding
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Protein Folding Chaperone
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
Metal Ion Binding
Protein Serine Kinase Activity
Transcription Regulator Activator Activity
Biological Process
RNA Splicing, Via Transesterification Reactions
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
MRNA Processing
Protein Folding
RNA Splicing
MiRNA Metabolic Process
Negative Regulation Of Low-density Lipoprotein Particle Clearance
Regulation Of MRNA Stability
Negative Regulation Of Nitric Oxide Biosynthetic Process
MRNA Transport
Positive Regulation Of MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
Cellular Response To Cytokine Stimulus
Neural Tube Formation
Endocardium Development
Protein Phosphorylation
Protein Import Into Nucleus
Apoptotic Process
Signal Transduction
JNK Cascade
Central Nervous System Development
Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Gene Expression
Organ Growth
Hippo Signaling
Positive Regulation Of Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of JNK Cascade
Negative Regulation Of Organ Growth
Epithelial Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Protein Stabilization
Protein Tetramerization
Centrosome Separation
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Canonical Wnt Signaling Pathway
Primitive Hemopoiesis
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of Cell Differentiation Involved In Embryonic Placenta Development
Protein Localization To Centrosome
Negative Regulation Of Canonical Wnt Signaling Pathway
Hepatocyte Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
KSRP (KHSRP) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Signaling by Hippo
Drugs
Resveratrol
Artenimol
Fostamatinib
Diseases
GWAS
Depressive symptom improvement (
30468137
)
Heel bone mineral density (
30598549
)
Rosacea symptom severity (
29771307
)
Suicide behavior (
26079190
)
Interacting Genes
17 interacting genes:
A1CF
APBB1
BACE1
CEBPA
EXOSC2
EXOSC3
GADD45A
GSK3B
HNRNPA1
HNRNPH1
MALAT1
NRON
PARN
PTBP2
SLC25A21-AS1
STK3
UBE2I
41 interacting genes:
AKT1
CASP3
CDK1
CNKSR1
CPNE1
DDAH2
EIF4EBP1
FAM9B
GABARAP
GABARAPL1
GAD1
GBP2
GMCL1
HSPE1
KEAP1
KHSRP
LATS2
LRRK2
MAP1LC3B
MAP1LC3C
MARK2
MBP
MOB3B
MOB4
MPP1
OGT
ORM2
PEX19
PIN1
QARS1
RAF1
RASSF4
SAV1
SLMAP
SNIP1
SULT2A1
TFPT
TRAF1
TRIM21
TRIM69
ZC3H7A
Entrez ID
8570
6788
HPRD ID
10350
05433
Ensembl ID
ENSG00000088247
ENSG00000104375
Uniprot IDs
M0R0C6
Q92945
A0A087WZ06
A0A384MR07
Q13188
PDB IDs
2HH2
2HH3
2JVZ
2OPU
2OPV
4B8T
3WWS
4HKD
4L0N
4LG4
4LGD
4OH9
5BRM
5DH3
6AO5
6AR2
8A66
Enriched GO Terms of Interacting Partners
?
Poly(A)-dependent SnoRNA 3'-end Processing
Sno(s)RNA Metabolic Process
MRNA Metabolic Process
3'-5'-RNA Exonuclease Activity
CUT Catabolic Process
Negative Regulation Of Macromolecule Metabolic Process
RNA Processing
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
TRAMP-dependent TRNA Surveillance Pathway
TRNA Surveillance
Nuclear Polyadenylation-dependent RRNA Catabolic Process
U4 SnRNA 3'-end Processing
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
RRNA 3'-end Processing
Nucleolar Exosome (RNase Complex)
RNA Metabolic Process
TRNA Decay
RNA 3'-end Processing
Cytoplasmic Exosome (RNase Complex)
RNA Exonuclease Activity
RNA Binding
Nucleic Acid Metabolic Process
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nuclear-transcribed MRNA Catabolic Process
Regulation Of Gene Expression
Positive Regulation Of Apoptotic Process
SnRNA 3'-end Processing
Positive Regulation Of Programmed Cell Death
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Telomere Maintenance Via Telomerase
Macromolecule Metabolic Process
Nucleic Acid Binding
MRNA Catabolic Process
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
SnRNA Processing
Nuclear RNA Surveillance
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
RNA Surveillance
Presynaptic Modulation Of Chemical Synaptic Transmission
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein
Regulation Of Microtubule Anchoring At Centrosome
Spliceosomal Complex
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of RNA Splicing
PriRNA 3'-end Processing
Cellular Response To Nitrogen Starvation
Autophagy Of Mitochondrion
Phosphatidylethanolamine Binding
Regulation Of Hippo Signaling
Cytoplasm
Mitophagy
Autophagosome
Cellular Response To Nutrient Levels
Autophagosome Assembly
Vacuole Organization
Cellular Response To Starvation
Autophagosome Organization
Regulation Of Intracellular Signal Transduction
Autophagy
Autophagosome Maturation
Positive Regulation Of Proteolysis
Intracellular Signal Transduction
Autophagosome Membrane
Response To Starvation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cytosol
Protein-containing Complex Disassembly
Negative Regulation Of Hippo Signaling
Hippo Signaling
Apoptotic Process
Macroautophagy
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Programmed Cell Death
Protein Binding
Cell Death
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Organ Growth
Signal Transduction
Protein-containing Complex Organization
Positive Regulation Of Protein Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Modification Process
Regulation Of Programmed Cell Death
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Response To Nutrient Levels
Response To Stress
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Pyroptotic Inflammatory Response
Regulation Of Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Proteasomal Protein Catabolic Process
Protein Serine Kinase Activity
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Tagcloud (Intersection)
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