POLR2M and MYO9A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	MYO9A
Gene Name		polymerase (RNA) II (DNA directed) polypeptide M	myosin IXA
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body	Cytosol Integral Component Of Membrane Unconventional Myosin Complex
	Molecular Function	DNA-directed RNA Polymerase Activity	Motor Activity Actin Binding GTPase Activator Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	RNA Biosynthetic Process Maintenance Of ER Location	Small GTPase Mediated Signal Transduction Visual Perception Metabolic Process Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Height ( 20881960) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	2 interactors: CDC42 POLR2M
Entrez ID		81488	4649
HPRD ID		07575	05341
Ensembl ID		ENSG00000255529	ENSG00000066933
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	B2RTY4
PDB IDs		2KXS
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process	Maintenance Of ER Location Positive Regulation Of Hair Follicle Cell Proliferation Endoplasmic Reticulum Localization Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Organelle Localization Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Regulation Of Protein Heterodimerization Activity Keratinocyte Development Regulation Of Synapse Structural Plasticity Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Golgi Localization Filopodium Assembly Hair Follicle Placode Formation Macrophage Differentiation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Dendritic Cell Migration Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Nucleus Localization Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Hair Follicle Morphogenesis Epithelial Cell-cell Adhesion Substantia Nigra Development Positive Regulation Of Cytokinesis Epidermis Morphogenesis Keratinization Salivary Gland Morphogenesis Nucleus Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Development Regulation Of Filopodium Assembly Negative Regulation Of ERBB Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Cell Fate Determination Skin Morphogenesis Neural Nucleus Development Organelle Transport Along Microtubule Sprouting Angiogenesis Regulation Of Cytokinesis Regulation Of Lipid Kinase Activity Exocrine System Development
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