POLR2M and WDR89

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	WDR89
Gene Name		polymerase (RNA) II (DNA directed) polypeptide M	WD repeat domain 89
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	DNA-directed RNA Polymerase Activity
	Biological Process	RNA Biosynthetic Process Maintenance Of ER Location
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	5 interactors: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		81488	112840
HPRD ID		07575	12635
Ensembl ID		ENSG00000255529
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	Q96FK6
PDB IDs		2KXS
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process	Maintenance Of ER Location Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Endoplasmic Reticulum Localization Defense Response Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling
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