POLR2M and UQCRQ

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	UQCRQ
Gene Name		polymerase (RNA) II (DNA directed) polypeptide M	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body	Mitochondrion Mitochondrial Inner Membrane Respiratory Chain
	Molecular Function	DNA-directed RNA Polymerase Activity	Ubiquinol-cytochrome-c Reductase Activity
	Biological Process	RNA Biosynthetic Process Maintenance Of ER Location	Subthalamus Development Pons Development Cerebellar Purkinje Cell Layer Development Hippocampus Development Thalamus Development Hypothalamus Development Pyramidal Neuron Development Respiratory Electron Transport Chain Midbrain Development Cellular Metabolic Process Small Molecule Metabolic Process Hydrogen Ion Transmembrane Transport
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	3 interactors: ERCC8 OPTN POLR2M
Entrez ID		81488	27089
HPRD ID		07575	17941
Ensembl ID		ENSG00000255529
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	O14949
PDB IDs		2KXS
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process	Maintenance Of ER Location Endoplasmic Reticulum Localization Negative Regulation Of Receptor Recycling Golgi Ribbon Formation Protein Targeting To Golgi Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Receptor Recycling Response To X-ray Golgi To Plasma Membrane Transport Positive Regulation Of DNA Repair Defense Response To Gram-negative Bacterium Transcription-coupled Nucleotide-excision Repair Protein Localization To Golgi Apparatus Protein Autoubiquitination
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